Oxidative Phospholipidomics in health and disease: Achievements, challenges and hopes
A Reis - Free Radical Biology and Medicine, 2017 - Elsevier
Phospholipid peroxidation products are recognized as important bioactive lipid mediators
playing an active role as modulators in signalling events in inflammation, immunity and …
playing an active role as modulators in signalling events in inflammation, immunity and …
Increased plasma oxidized phospholipid: apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary …
S Tsimikas, M Aikawa, FJ Miller Jr… - … , and vascular biology, 2007 - Am Heart Assoc
Background—Oxidized phospholipids (OxPL) are pro-inflammatory. We evaluated whether
changes in plasma levels of OxPL associated with apolipoprotein B-100 (apoB-100) reflect …
changes in plasma levels of OxPL associated with apolipoprotein B-100 (apoB-100) reflect …
Inflammatory and atherogenic effects of oxidized phospholipids
GB Lim - Nature Reviews Cardiology, 2018 - nature.com
“Wherever you get inflammation, you get oxidized phospholipids (ox-Pls),” says Joseph
Witztum, senior author of a new study published in Nature. Witztum and colleagues now …
Witztum, senior author of a new study published in Nature. Witztum and colleagues now …
Oxidized phospholipids as a new landmark in atherosclerosis
H Itabe - Progress in lipid research, 1998 - Elsevier
It is thought that high concentrations of plasma low density lipoprotein (LDL) are correlated
with the occurrence of atherosclerosis. Although no intimal thickening is observed in the …
with the occurrence of atherosclerosis. Although no intimal thickening is observed in the …
Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids
SS Davies, L Guo - Chemistry and physics of lipids, 2014 - Elsevier
Peroxidation of membranes and lipoproteins converts “inert” phospholipids into a plethora of
oxidatively modified phospholipids (oxPL) that can act as signaling molecules. In this review …
oxidatively modified phospholipids (oxPL) that can act as signaling molecules. In this review …
Lipid peroxidation in atherosclerotic cardiovascular diseases
E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …
Oxidation-specific biomarkers and risk of peripheral artery disease
ML Bertoia, JK Pai, JH Lee, A Taleb… - Journal of the American …, 2013 - jacc.org
Objectives: The goal of this study was to examine the prospective association between
oxidation-specific biomarkers, primarily oxidized phospholipids (OxPL) on apolipoprotein B …
oxidation-specific biomarkers, primarily oxidized phospholipids (OxPL) on apolipoprotein B …
Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin …
AE Fraley, GG Schwartz, AG Olsson, S Kinlay… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to define the relationship between oxidative biomarkers,
cardiovascular disease (CVD) risk factors, and inflammatory and thrombosis biomarkers …
cardiovascular disease (CVD) risk factors, and inflammatory and thrombosis biomarkers …
Oxidized phospholipids: emerging lipid mediators in pathophysiology
HP Deigner, A Hermetter - Current opinion in lipidology, 2008 - journals.lww.com
Recent studies shed some light on oxidized phospholipid-induced signalling with regard to
apoptosis, gene expression and receptor-mediated events. They support the notion that the …
apoptosis, gene expression and receptor-mediated events. They support the notion that the …
Oxidized phospholipids, lipoprotein (a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck …
S Kiechl, J Willeit, M Mayr, B Viehweider… - … , and vascular biology, 2007 - Am Heart Assoc
Background—Oxidized phospholipids (OxPL) circulate on apolipoprotein B-100 particles
(OxPL/apoB), and primarily on Lp (a) lipoprotein (a)[Lp (a)]. The relationship of OxPL/apoB …
(OxPL/apoB), and primarily on Lp (a) lipoprotein (a)[Lp (a)]. The relationship of OxPL/apoB …