Oxidized phospholipids (OxPL) are key mediators of the pro-atherosclerotic effects of
oxidized lipoproteins. They are particularly important for the pathogenicity of lipoprotein …

AIMS: OxPL are pro-inflammatory and may mediate atherogenesis, thrombosis and
endothelial dysfunction. We studied the histological presence and temporal increases in …

Bioactive lipids have taken the center stage in the last decade as dynamic mediators of
cellular signaling and regulation. Lipids can directly and indirectly modify cellular processes …

Background Biomarkers to predict recurrent stroke and targets of therapy to prevent stroke
are lacking. Objectives This study evaluated whether patients with prior cerebrovascular …

Atherosclerosis is a multifactorial disease, where more than one mechanism, along more
than one step, contributes to macrophage cholesterol accumulation and foam cell formation …

Oxidized LDL (OxLDL) is a proatherogenic lipoprotein, accumulating in the vascular wall
and contributing to the pathogenesis of vascular dysfunction early in the development of …

Background—Plasma level of oxidized low-density lipoprotein (OxLDL) is a risk marker for
cardiovascular diseases. The behavior of plasma OxLDL before disease progression has …

Isolevuglandins (isoLGs) and oxidatively truncated phospholipids are products of lipid
peroxidation. Some of these, especially isoLGs and γ‐hydroxyalkenal analogues (eg, the 5 …

Inflammation and lipid peroxidation are interrelated processes contributing to atherogenesis.
Thus, antiinflammatory and antioxidant agents can attenuate, under certain conditions (but …

The levels of circulating oxidized phospholipids (OxPLs) become increased in chronic and
acute pathologic conditions such as hyperlipidemia, atherosclerosis, increased intimamedia …