A natural history model for planning prostate cancer testing: calibration and validation using Swedish registry data

A Karlsson, A Jauhiainen, R Gulati, M Eklund… - PLoS …, 2019 - journals.plos.org
Recent prostate cancer screening trials have given conflicting results and it is unclear how to
reduce prostate cancer mortality while minimising overdiagnosis and overtreatment …

Benefits and harms of prostate specific antigen testing according to Australian guidelines

M Caruana, R Gulati, R Etzioni, A Barratt… - … Journal of Cancer, 2024 - Wiley Online Library
Guidelines for prostate specific antigen (PSA) testing in Australia recommend that men at
average risk of prostate cancer who have been informed of the benefits and harms, and who …

Lifetime benefits and harms of prostate-specific antigen–based risk-stratified screening for prostate cancer

EAM Heijnsdijk, R Gulati, A Tsodikov… - JNCI: Journal of the …, 2020 - academic.oup.com
Abstract Background Studies conducted in Swedish populations have shown that men with
lowest prostate-specific antigen (PSA) levels at ages 44–50 years and 60 years have very …

Variation in prostate-specific antigen testing rates and prostate cancer treatments and outcomes in a national 20-year cohort

O Bergengren, M Westerberg, L Holmberg… - JAMA network …, 2021 - jamanetwork.com
Importance The diagnostic activity for prostate cancer has increased during the past
decades. However, the benefit and harm of the increased diagnostic activity have not been …

How does early detection by screening affect disease progression? Modeling estimated benefits in prostate cancer screening

EM Wever, G Draisma, EAM Heijnsdijk… - Medical Decision …, 2011 - journals.sagepub.com
Background. Simulation models are essential tools for estimating benefits of cancer
screening programs. Such models include a screening-effect model that represents how …

Poor follow-up after elevated prostate-specific antigen tests: a population-based cohort study

M Aly, M Clements, CE Weibull, T Nordström… - European Urology …, 2019 - Elsevier
Background Although prostate-specific antigen (PSA) testing is common, little is known
about the pattern of retesting by either PSA values or subsequent prostate biopsies. Poor …

Incidence of prostate cancer after termination of screening in a population-based randomised screening trial

AG Bergdahl, E Holmberg, S Moss, J Hugosson - European urology, 2013 - Elsevier
Background In a previous publication from the Göteborg randomised screening trial from
2010, biennial prostate-specific antigen (PSA) screening for men≤ 69 yr of age was shown …

What if I don't treat my PSA-detected prostate cancer? Answers from three natural history models

R Gulati, EM Wever, A Tsodikov, DF Penson… - … , biomarkers & prevention, 2011 - AACR
Background: Making an informed decision about treating a prostate cancer detected after a
routine prostate-specific antigen (PSA) test requires knowledge about disease natural …

[HTML][HTML] Correlation between stage shift and differences in mortality in the European Randomized study of Screening for Prostate Cancer (ERSPC)

LP Bokhorst, M Zappa, SV Carlsson… - BJU …, 2016 - ncbi.nlm.nih.gov
Abstract A 21% prostate cancer (PCa) mortality reduction was observed in the European
Randomized Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up. A …

Cost-effectiveness of prostate cancer screening: a systematic review of decision-analytical models

S Sanghera, J Coast, RM Martin, JL Donovan… - BMC cancer, 2018 - Springer
Background There is ongoing debate about the harms and benefits of a national prostate
cancer screening programme. Several model-based cost-effectiveness analyses have been …