Cryo-electron tomography (CryoET) images the cellular environment in situ, without labels,
and with fully preserved context. However, the complex cellular environment and the low …

Cryo-focused ion beam milling of frozen-hydrated cells and subsequent cryo-electron
tomography (cryo-ET) has enabled the structural elucidation of macromolecular complexes …

Cryo-electron tomography is the highest resolution tool available for structural analysis of
macromolecular complexes within their native cellular environments. At present, data …

Cryo-electron tomography (cryo-ET) provides a promising approach to study intact structures
of macromolecules in situ, but the efficient preparation of high-quality cryosections …

The combination of increasing resolution in cryo-electron microscopy (cryo-EM) and sample
preparation using cryo-focused ion beam (FIB) milling has enabled visualization of …

In situ cryo electron tomography of cryo focused ion beam milled samples has emerged in
recent years as a powerful technique for structural studies of macromolecular complexes in …

Cryo-electron tomography (cryoET) is a powerful technology that allows in-situ observation
of the molecular structure of tissues and cells. Cryo-focused ion beam (cryoFIB) milling plays …

Cryogenic electron microscopy and data processing enable the determination of structures
of isolated macromolecules to near-atomic resolution. However, these data do not provide …

Cryo‐electron tomography (cryo‐ET) provides high‐resolution 3D views into cells pristinely
preserved by vitrification. Recent technical advances such as direct electron detectors, the …

Cryogenic electron tomography (cryo-ET) combined with subtomogram averaging, allows in
situ visualization and structure determination of macromolecular complexes at …