Ketamine is a dissociative anesthetic agent used routinely for more than 40 years in human
anesthesiology (7). It is particularly useful in conditions in which cardiovascular and …

Ketamine has been available for approximately 50 years as an anesthetic agent. It is known
to have potent effects on the central nervous system glutamatergic system, in particular …

Ketamine is an anesthetic drug that is also used for off-label indications such as the
mediation of analgesia and sedation in various settings. It is additionally recognized as an …

Since publication of the first randomized controlled trial describing rapid antidepressant
effects of ketamine, several reports have confirmed the potential utility of this dissociative …

Since publication of the first randomized controlled trial describing rapid antidepressant
effects of ketamine, several reports have confirmed the potential utility of this dissociative …

Recent reports of an acute antidepressant effect for intravenous ketamine, a schedule III
agent used in anesthesia and pain clinics, have generated considerable hope and …

Discussion This is the first trial of ketamine given by the SC route for the treatment of
depression, showing excellent outcomes. In this patient, a single dose of ketamine …

Background: Ketamine, administered in subanesthetic doses, is an effective off-label
treatment for severe and even treatment-refractory depression; however, despite dozens of …

In this review, we will discuss the safety of repeated treatments with ketamine for patients
with treatment-resistant depression (TRD), a condition in which patients with major …

The oral route of administration is probably the least expensive and most convenient way to
administer ketamine in indicated contexts in depressed patients. Because only 20%-25% of …