[PDF][PDF] Poly (alkyl cyanoacrylate) nanoparticles as drug carriers: 33 years later

G Yordanov - Bulg J Chem, 2012 - researchgate.net
First prepared in 1979, the colloidal nanoparticles based on biocompatible and bioerosive
poly (alkyl cyanoacrylate) materials are still under investigation and hold promise for the …

Synthesis of poly (alkyl cyanoacrylate)‐based colloidal nanomedicines

J Nicolas, P Couvreur - Wiley Interdisciplinary Reviews …, 2009 - Wiley Online Library
Nanoparticles developed from poly (alkyl cyanoacrylate)(PACA) biodegradable polymers
have opened new and exciting perspectives in the field of drug delivery due to their nearly …

Poly (Alkyl Cyanoacrylate) Nanosystems

J Nicolas, C Vauthier - Intracellular Delivery: Fundamentals and …, 2011 - Springer
Poly (alkyl cyanoacrylate) nanosystems include various types of nanoparticles suitable to
achieve in vivo drug delivery in a well controlled manner. Starting from general features on …

Design aspects of poly (alkylcyanoacrylate) nanoparticles for drug delivery

C Vauthier, D Labarre, G Ponchel - Journal of drug targeting, 2007 - Taylor & Francis
Poly (alkylcyanoacrylate)(PACA) nanoparticles were first developed 25 years ago taking
advantage of the in vivo degradation potential of the polymer and of its good acceptance by …

Novel polysaccharide-decorated poly (isobutyl cyanoacrylate) nanoparticles

C Chauvierre, D Labarre, P Couvreur… - Pharmaceutical …, 2003 - Springer
Purpose. The aim of this work was to synthesize new surface-modified nanoparticles using a
radical emulsion polymerization of an alkyl cyanoacrylate. Methods. Isobutyl cyanoacrylate …

Polyalkylcyanoacrylates as colloidal drug carriers.

P Couvreur - Critical reviews in therapeutic drug carrier systems, 1988 - europepmc.org
A considerable amount of energy has been spent in creating new colloidal drug delivery
systems that are acceptable for general systemic use. Among these new systems …

Evaluation of polyalkylcyanoacrylate nanoparticles as a potential drug carrier: preparation, morphological characterization and loading capacity

G Puglisi, G Giammona, M Fresta, B Carlisi… - Journal of …, 1993 - Taylor & Francis
Some physicochemical behaviours were investigated of polyethyl-(PECA) and
polyisobutylcyanoacrylate (PICA), which, in recent years, have been proposed as …

Entrapment of bioactive molecules in poly (alkylcyanoacrylate) nanoparticles

K Krauel, T Pitaksuteepong, NM Davies… - American Journal of Drug …, 2004 - Springer
Abstract Poly (alkylcyanoacrylate)[PACA] nanoparticles have been studied since the early
1980s as possible colloidal drug delivery systems. Several excellent general reviews have …

Core-shell type of nanoparticles composed of poly [(n-butyl cyanoacrylate)-co-(2-octyl cyanoacrylate)] copolymers for drug delivery application: synthesis …

CY Huang, YD Lee - International journal of pharmaceutics, 2006 - Elsevier
Core-shell type of nanoparticles (NPs) with manipulated degradation rate and balanced
hydrophilic/hydrophobic properties were designed and characterized. The NPs based on …

(Poly-cyanoacrylate) nanomedicines for cancer and beyond: Lessons learned

P Couvreur - Journal of Controlled Release, 2021 - Elsevier
Abstract This «Magnum Opus» emphasizes that serendipity is a corner stone in research.
The paths of discovery and innovation often result from the interdisciplinarity of scientific …