Pancreatic stellate cells increase pancreatic cancer cells invasion through the hepatocyte growth factor/c-Met/survivin regulated by P53/P21
XP Yang, SL Liu, JF Xu, SG Cao, Y Li… - Experimental cell research, 2017 - Elsevier
Pancreatic stellate cells (PSCs) are a key cellular component of the pancreatic tumor
microenvironment and are considered to contribute to tumor invasion and metastasis …
microenvironment and are considered to contribute to tumor invasion and metastasis …
Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells
K Kikuta, A Masamune, T Watanabe, H Ariga… - Biochemical and …, 2010 - Elsevier
The interaction between pancreatic cancer cells and pancreatic stellate cells (PSCs), a
major profibrogenic cell type in the pancreas, is receiving increasing attention. There is …
major profibrogenic cell type in the pancreas, is receiving increasing attention. There is …
Pancreatic stellate cells facilitate pancreatic cancer cell viability and invasion
SL Liu, SG Cao, Y Li, B Sun, D Chen… - Oncology …, 2019 - spandidos-publications.com
The biological features of pancreatic cancer and the associated hypoxic environment
around the cancer cells often lead to resistance to radiotherapy and chemotherapy. The …
around the cancer cells often lead to resistance to radiotherapy and chemotherapy. The …
Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells
S Hamada, A Masamune, T Takikawa, N Suzuki… - Biochemical and …, 2012 - Elsevier
The interaction between pancreatic cancer cells and pancreatic stellate cells (PSCs), a
major profibrogenic cell type in the pancreas, is receiving increasing attention. There is …
major profibrogenic cell type in the pancreas, is receiving increasing attention. There is …
Paracrine HGF promotes EMT and mediates the effects of PSC on chemoresistance by activating c-Met/PI3K/Akt signaling in pancreatic cancer in vitro
J Xu, S Liu, X Yang, S Cao, Y Zhou - Life Sciences, 2020 - Elsevier
Abstract Background Pancreatic stellate cells (PSCs) play key roles in the pancreatic tumor
microenvironment and are considered to contribute to chemoresistance. PSCs can …
microenvironment and are considered to contribute to chemoresistance. PSCs can …
Pancreatic stellate cells: partners in crime with pancreatic cancer cells
Pancreatic stellate cells (PSC) produce the stromal reaction in pancreatic cancer, but their
role in cancer progression is not fully elucidated. We examined the influence of PSCs on …
role in cancer progression is not fully elucidated. We examined the influence of PSCs on …
Pancreatic stellate cells facilitate perineural invasion of pancreatic cancer via HGF/c-Met pathway
L Nan, T Qin, Y Xiao, W Qian, J Li, Z Wang… - Cell …, 2019 - journals.sagepub.com
Pancreatic cancer (PC) is a highly lethal cancer that has a strong ability for invasion and
metastasis, poor prognosis, and a stubbornly high death rate due to late diagnosis and early …
metastasis, poor prognosis, and a stubbornly high death rate due to late diagnosis and early …
[HTML][HTML] Fibroblast activation protein α-positive pancreatic stellate cells promote the migration and invasion of pancreatic cancer by CXCL1-mediated Akt …
Z Wen, Q Liu, J Wu, B Xu, J Wang, L Liang… - Annals of …, 2019 - ncbi.nlm.nih.gov
Background Pancreatic stellate cells (PSCs) is a highly heterogeneic stroma cell population
in pancreatic cancer tissue. Interaction between PSCs and pancreatic cancer cells has not …
in pancreatic cancer tissue. Interaction between PSCs and pancreatic cancer cells has not …
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α
B Yan, Z Jiang, L Cheng, KE Chen, C Zhou… - Experimental cell …, 2018 - Elsevier
Pancreatic stellate cells (PSCs), a pivotal component of the tumor microenvironment,
contribute to tumor growth and metastasis. PSC-derived factors are essential for triggering …
contribute to tumor growth and metastasis. PSC-derived factors are essential for triggering …
Pancreatic stellate cells–multi-functional cells in the pancreas
A Masamune, T Shimosegawa - Pancreatology, 2013 - Elsevier
There is accumulating evidence that activated pancreatic stellate cells (PSCs) play a pivotal
role in pancreatic fibrosis in chronic pancreatitis and pancreatic cancer. In addition, we have …
role in pancreatic fibrosis in chronic pancreatitis and pancreatic cancer. In addition, we have …