[HTML][HTML] Clinical manifestation and management of amyotrophic lateral sclerosis

A Verma - 2021 - europepmc.org
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease
resulting in death in 2 to 4 years in most cases. There are several clinical subtypes of ALS …

Diagnosis and clinical management of amyotrophic lateral sclerosis and other motor neuron disorders

SA Goutman - CONTINUUM: Lifelong Learning in Neurology, 2017 - journals.lww.com
Abstract Purpose of Review: This article reviews the clinical features, diagnostic pathway,
therapies, and current understanding of the pathophysiology of amyotrophic lateral sclerosis …

The panoramic view of amyotrophic lateral sclerosis: A fatal intricate neurological disorder

S Dhasmana, A Dhasmana, AS Narula, M Jaggi… - Life Sciences, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …

[HTML][HTML] Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies

LM Gittings, R Sattler - Faculty reviews, 2020 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is
characterized by degeneration of both upper and lower motor neurons and subsequent …

ALS update: Signs of progress, reasons for hope

RS Bedlack, S Aggarwal - CONTINUUM: Lifelong Learning in …, 2009 - journals.lww.com
Amyotrophic lateral sclerosis (ALS) was first described 134 years ago. While still incurable,
significant progress has been made in understanding the pathophysiology of the disease …

Recent advances in amyotrophic lateral sclerosis

N Riva, F Agosta, C Lunetta, M Filippi, A Quattrini - Journal of neurology, 2016 - Springer
ALS is a relentlessly progressive and fatal disease, with no curative therapies available to
date. Symptomatic and palliative care, provided in a multidisciplinary context, still remains …

Moving toward a predictive and personalized clinical approach in amyotrophic lateral sclerosis: novel developments and future directions in diagnosis, genetics …

B Nefussy, VE Drory - EPMA Journal, 2010 - Springer
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that affects upper
and lower motor neurons in the brain and spinal cord, with progressive weakness and …

Amyotrophic lateral sclerosis

PM Andersen, GD Borasio, R Dengler… - European Handbook …, 2006 - Wiley Online Library
Background Despite being one of the most devastating diseases known, there is little
evidence for diagnosing and managing patients with amyotrophic lateral sclerosis (ALS) …

Amyotrophic lateral sclerosis–looking for pathogenesis and effective therapy

E Naganska, E Matyja - Folia Neuropathologica, 2011 - termedia.pl
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …

[HTML][HTML] Challenges in the understanding and treatment of amyotrophic lateral sclerosis/motor neuron disease

J Rosenfeld, MJ Strong - Neurotherapeutics, 2015 - Elsevier
With the acceleration in our understanding of ALS and the related motor neuron disease has
come even greater challenges in reconciling all of the proposed pathogenic mechanisms …