Galectin-9 and Interferon-Gamma Are Released by Natural Killer Cells upon Activation with Interferon-Alpha and Orchestrate the Suppression of Hepatitis C Virus …
Natural killer (NK) cells mount an immune response against hepatitis C virus (HCV) infection
and can be activated by several cytokines, including interleukin-2 (IL-2), IL-15, and …
and can be activated by several cytokines, including interleukin-2 (IL-2), IL-15, and …
Galectin-9 functionally impairs natural killer cells in humans and mice
Galectin-9 is a pleiotropic immune modulator affecting numerous cell types of innate and
adaptive immunity. Patients with chronic infection with either hepatitis C virus (HCV) or HIV …
adaptive immunity. Patients with chronic infection with either hepatitis C virus (HCV) or HIV …
Interferon α–stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX …
KA Stegmann, NK Björkström, S Ciesek… - Journal of Infectious …, 2012 - academic.oup.com
Background. Natural killer (NK) cells are an important component of the innate immune
defense against viruses, including hepatitis C virus (HCV). The cell culture system using …
defense against viruses, including hepatitis C virus (HCV). The cell culture system using …
Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication
E Serti, JM Werner, M Chattergoon, AL Cox… - Gastroenterology, 2014 - Elsevier
Background & Aims Production of interferon (IFN)-γ by natural killer (NK) cells is attenuated
during chronic infection with hepatitis C virus (HCV). We investigated whether this is due to …
during chronic infection with hepatitis C virus (HCV). We investigated whether this is due to …
[HTML][HTML] Natural killer cells in viral hepatitis
B Rehermann - Cellular and molecular gastroenterology and …, 2015 - Elsevier
Natural killer (NK) cells are traditionally regarded as first-line effectors of the innate immune
response, but they also have a distinct role in chronic infection. Here, we review the role of …
response, but they also have a distinct role in chronic infection. Here, we review the role of …
Natural Cytotoxicity Receptor–Dependent Natural Killer Cytolytic activity Directed at Hepatitis C Virus (HCV) Is Associated With Liver Inflammation, African American …
Q Meng, MRS Rani, JM Sugalski… - The Journal of …, 2014 - academic.oup.com
Background. Natural killer (NK) cells are implicated in the pathogenesis of hepatitis C virus
(HCV) infection and outcome of interferon (IFN)-α based therapy, although mechanisms …
(HCV) infection and outcome of interferon (IFN)-α based therapy, although mechanisms …
[PDF][PDF] Natural killer cells and hepatitis C: natural killer p46 expression linked to antiviral and antifibrotic activity
M Heeg, R Thimme - Hepatology, 2012 - Wiley Online Library
Natural killer (NK) cells play an important role in innate immune response and are essential
in the host's first-line defense against viral infections. A major hallmark of NK cells is their …
in the host's first-line defense against viral infections. A major hallmark of NK cells is their …
[PDF][PDF] CD14+ monocyte‐derived galectin‐9 induces natural killer cell cytotoxicity in chronic hepatitis C
A Nishio, T Tatsumi, T Nawa, T Suda, T Yoshioka… - …, 2017 - Wiley Online Library
Natural killer (NK) cell activation is associated with both liver injury and persistent infection
in chronic hepatitis C (CHC); however, the detailed mechanism of this activation has not yet …
in chronic hepatitis C (CHC); however, the detailed mechanism of this activation has not yet …
IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells
S Zhang, B Saha, K Kodys, G Szabo - Journal of hepatology, 2013 - Elsevier
Background & Aims Interferon-γ (IFN-γ), a cytokine produced by activated natural killer cells
(NK) and T lymphocytes, is an important regulator of innate and adaptive immunity during …
(NK) and T lymphocytes, is an important regulator of innate and adaptive immunity during …
[PDF][PDF] Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver …
B Krämer, C Körner, M Kebschull, A Glässner… - …, 2012 - Wiley Online Library
Natural killer (NK) cells play a role in the early control and natural course of hepatitis C virus
(HCV) infection. NK cell function is regulated by a multitude of receptors, including activating …
(HCV) infection. NK cell function is regulated by a multitude of receptors, including activating …