[HTML][HTML] Multiparametric PET and MRI of myocardial damage after myocardial infarction: correlation of integrin αvβ3 expression and myocardial blood flow

MR Makowski, C Rischpler, U Ebersberger… - European Journal of …, 2021 - Springer
Purpose Increased angiogenesis after myocardial infarction is considered an important
favorable prognostic parameter. The αvβ3 integrin is a key mediator of cell-cell and cell …

Assessment of αvβ3 integrin expression after myocardial infarction by positron emission tomography

T Higuchi, FM Bengel, S Seidl… - Cardiovascular …, 2008 - academic.oup.com
Aims The purpose of this study was to determine the feasibility of a new positron emission
tomography (PET) imaging approach using an 18F-labelled αvβ3 integrin antagonist (18F …

Molecular imaging of early αvβ3 integrin expression predicts long-term left-ventricle remodeling after myocardial infarction in rats

HM Sherif, A Saraste, SG Nekolla, E Weidl… - Journal of Nuclear …, 2012 - Soc Nuclear Med
18F-galacto-RGD (18F-RGD) is a PET tracer binding to αvβ3 integrin receptors that are
upregulated after myocardial infarction (MI) as part of the healing process. We studied …

PET imaging of angiogenesis after myocardial infarction/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2

H Gao, L Lang, N Guo, F Cao, Q Quan, S Hu… - European journal of …, 2012 - Springer
Purpose The α v β 3 integrin represents a potential target for noninvasive imaging of
angiogenesis. The purpose of this study was to evaluate a novel one-step labeled integrin α …

In vivo molecular imaging of angiogenesis, targeting αvβ3 integrin expression, in a patient after acute myocardial infarction

MR Makowski, U Ebersberger, S Nekolla… - European heart …, 2008 - academic.oup.com
A 35-year-old Caucasian male presented with chest pain and nausea in the emergency
room. The initial ECG displayed sinus-rhythm with ST elevation in I, aVL, V1–5, ST …

[HTML][HTML] Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

M Grönman, M Tarkia, T Kiviniemi, P Halonen… - Journal of Translational …, 2017 - Springer
Background Radiolabeled RGD peptides detect α v β 3 integrin expression associated with
angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied …

[HTML][HTML] Application of 68Ga-PRGD2 PET/CT for αvβ3-integrin imaging of myocardial infarction and stroke

Y Sun, Y Zeng, Y Zhu, F Feng, W Xu, C Wu, B Xing… - Theranostics, 2014 - ncbi.nlm.nih.gov
Purpose: Ischemic vascular diseases, including myocardial infarction (MI) and stroke, have
been found to be associated with elevated expression of α v β 3-integrin, which provides a …

Evaluation of a Novel 18F-Labeled Positron-Emission Tomography Perfusion Tracer for the Assessment of Myocardial Infarct Size in Rats

HM Sherif, A Saraste, E Weidl, AW Weber… - Circulation …, 2009 - Am Heart Assoc
Background—The goal of this study was to evaluate a new 18F-labeled positron-emission
tomography (PET) perfusion tracer, 18F BMS747158-02, for the assessment of myocardial …

Targeting post-infarct inflammation by PET imaging: comparison of 68Ga-citrate and 68Ga-DOTATATE with 18F-FDG in a mouse model

JT Thackeray, JP Bankstahl, Y Wang… - European journal of …, 2015 - Springer
Methods C57Bl/6 mice underwent permanent coronary artery ligation. Serial PET imaging
was performed 3–7 days after MI using 68 Ga-citrate, 68 Ga-DOTATATE, or 18 F-FDG with …

Cardiac αVβ3 integrin expression following acute myocardial infarction in humans

WSA Jenkins, AT Vesey, C Stirrat, M Connell… - Heart, 2017 - heart.bmj.com
Objective Maladaptive repair contributes towards the development of heart failure following
myocardial infarction (MI). The αvβ3 integrin receptor is a key mediator and determinant of …