Alpha-lipoic acid-mediated activation of muscarinic receptors improves hippocampus-and amygdala-dependent memory

A Mahboob, SM Farhat, G Iqbal, MM Babar… - Brain research …, 2016 - Elsevier
Aluminum (Al) is a neurotoxic agent which readily crosses the blood-brain-barrier (BBB) and
accumulates in the brain leading to neurodegenerative disorders, characterised by cognitive …

Docosahexaenoic acid suppresses neuroinflammatory responses and induces heme oxygenase-1 expression in BV-2 microglia: implications of antidepressant effects …

DY Lu, YY Tsao, YM Leung, KP Su - Neuropsychopharmacology, 2010 - nature.com
Accumulating evidence suggests that the pathophysiology of depression might be
associated with neuroinflammation, which could be attenuated by pharmacological …

Efficacy of dl-α-lipoic acid on methanol induced free radical changes, protein oxidative damages and hsp70 expression in folate deficient rat nervous tissue

R Rajamani, A Muthuvel, S Manikandan… - Chemico-biological …, 2007 - Elsevier
dl-α-Lipoic acid (LPA) was reported to be effective in reducing free radicals generated by
oxidative stress. The protective of effect of LPA on methanol (MeOH) induced free radical …

[HTML][HTML] Alleviative effect of alpha-lipoic acid on cognitive impairment in high-fat diet and streptozotocin-induced type 2 diabetic rats

CY Ko, JH Xu, YM Lo, RS Tu, JSB Wu… - Frontiers in Aging …, 2021 - frontiersin.org
Background: The intricate relationship between type 2 diabetes mellitus (T2DM) and
Alzheimer's disease (AD) suggests that insulin is involved in modulating AD-related …

Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice

VN Thakare, VD Dhakane, BM Patel - Metabolic brain disease, 2017 - Springer
Protocatechuic acid ethyl ester (PCA), a phenolic compound, exhibits neuroprotective effects
through improving endogenous antioxidant enzymatic and nonezymatic system. Based on …

Systemic administration of oleoylethanolamide protects from neuroinflammation and anhedonia induced by LPS in rats

A Sayd, M Antón, F Alén, JR Caso… - International Journal …, 2015 - academic.oup.com
Background: The acylethanolamides oleoylethanolamide and palmitoylethanolamide are
endogenous lipid mediators with proposed neuroprotectant properties in central nervous …

Antidepressant and neuroprotective effects of naringenin via sonic hedgehog-GLI1 cell signaling pathway in a rat model of chronic unpredictable mild stress

M Tayyab, S Farheen, N Khanam… - Neuromolecular …, 2019 - Springer
Depression is one of the most prevalent and crucial public health problem connected to
significant mortality and co-morbidity. Recently, numerous studies suggested that dietary …

Perilla aldehyde attenuates CUMS-induced depressive-like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats

Y Song, R Sun, Z Ji, X Li, Q Fu, S Ma - Life sciences, 2018 - Elsevier
Background Current evidence supports that inflammatory reaction in the hippocampus is a
potential cause of major depressive disorder (MDD). Perilla aldehyde (PAH), a major …

Tauroursodeoxycholic acid produces antidepressant‐like effects in a chronic unpredictable stress model of depression via attenuation of neuroinflammation, oxido …

XU Lu, RR Yang, JL Zhang, P Wang… - Fundamental & …, 2018 - Wiley Online Library
Depression is a common psychiatric disorder with heavy economic and social burdens.
Searching new agents with better antidepressant‐like activities is of great significance for …

[PDF][PDF] Protective effects of Olive oil on the stress induced behavioral changes in rats

T Perveen, S Qadeer, S Emad, S Sadaf… - Pak. J. Biochem. Mol …, 2016 - pjbmb.org.pk
The objective of the current study was to examine protective effects of olive oil having high
magnitude of essential components and likely to guard the brain from damaging outcomes …