Esophageal injuries such as partial-thickness defects from mucosal resections can result in
fibrosis and refractory strictures. Similarly, full-thickness patch defects like perforations can …

Advances in tissue engineering techniques have made it possible to use human cells as
biological material. This has enabled pharmacological studies to be conducted to …

Pathologies that involve the structure and/or function of the esophagus can be life-
threatening. The esophagus is a complex organ comprising nonredundant tissue that does …

Presently, the standard of care for esophageal diseases employs surgical techniques that
utilize either primary anastomotic repairs or the use of stomach and intestinal conduits for …

For various esophageal diseases, the search for alternative techniques for tissue repair has
led to significant developments in basic and translational research in the field of tissue …

The current treatments for esophageal diseases, such as carcinomas, trauma or congenital
malformations, require surgical intervention and esophageal reconstruction using redundant …

A number of congenital and acquired disorders require esophageal tissue replacement.
Various surgical techniques, such as gastric and colonic interposition, are standards of …

The diseases of the esophagus include congenital defects like atresia, tracheoesophageal
fistula as well as others such as gastro-esophageal reflux disease (GERD), Barrett's …

Tissue engineering, which consists of the combination and in vivo implantation of elements
required for tissue remodeling toward a specific organ phenotype, could be an alternative for …

Long-gap esophageal defects, whether congenital or acquired, are very difficult to manage.
Any significant surgical peri-esophageal dissection that is performed to allow for potential …