Esophageal reconstruction through bio-engineered allografts that highly resemble the
peculiar properties of the tissue extracellular matrix (ECM) is a prospective strategy to …

As a result of injury caused by chronic gastroesophageal reflux, Barrett's esophagus with
high-grade dysplasia and esophageal adenocarcinoma are rapidly increasing problems in …

Biologic scaffolds composed of extracellular matrix (ECM) are commonly used to facilitate a
constructive remodeling response in several types of tissue, including the esophagus …

For reconstruction of esophageal defects the conventional methods include pedicled
stomach or gastric tube, pedicled colon segment interposition, pedicled skin or …

We have been conducting research on esophageal regenerative therapy using cell sheet
technology. In particular, in the endoscopic field, we have pushed forward clinical research …

Although total parenteral nutrition prevents patients with short bowel syndrome from dying of
starvation, having short bowel remains a severely debilitating condition. The best current …

The progress of tissue-engineering technology has realized development of new therapies
to treat various disorders by using cultured cells. Cell-and tissue-based therapies have been …

We manufactured an esophageal prosthesis made of a collagen sponge supported by an
inner silicone tube. The collagen was derived from porcine skin and was crosslinked by …

Introduction Resection and reconstruction of the esophagus remains fraught with morbidity
and mortality. Recently, data from a porcine reconstruction model revealed that segmental …

Objective Esophagus tissue engineering holds promises to overcome the limitations of the
presently employed esophageal replacement procedures. This study investigated 5 animal …