Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release

N Romano, SH Yip, DJ Hodson, A Guillou… - Journal of …, 2013 - Soc Neuroscience
Tuberoinfundibular dopamine (TIDA) neurons are the central regulators of prolactin (PRL)
secretion. Their extensive functional plasticity allows a change from low PRL secretion in the …

[PDF][PDF] Synchronized network oscillations in rat tuberoinfundibular dopamine neurons: switch to tonic discharge by thyrotropin-releasing hormone

DJ Lyons, E Horjales-Araujo, C Broberger - Neuron, 2010 - cell.com
The pituitary hormone, prolactin, triggers lactation in nursing mothers. Under nonlactating
conditions, prolactin secretion is suppressed by powerful inhibition from hypothalamic …

[PDF][PDF] Elevated prolactin during pregnancy drives a phenotypic switch in mouse hypothalamic dopaminergic neurons

SH Yip, N Romano, P Gustafson, DJ Hodson… - Cell reports, 2019 - cell.com
Altered physiological states require neuronal adaptation. In late pregnancy and lactation, a
sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons …

TIDAL WAVES: network mechanisms in the neuroendocrine control of prolactin release

DJ Lyons, C Broberger - Frontiers in neuroendocrinology, 2014 - Elsevier
Neuroendocrine tuberoinfundibular dopamine (TIDA) neurons tonically inhibit pituitary
release of the hormone, prolactin. Through the powerful actions of prolactin in promoting …

Prolactin regulates tuberoinfundibular dopamine neuron discharge pattern: novel feedback control mechanisms in the lactotrophic axis

DJ Lyons, A Hellysaz, C Broberger - Journal of Neuroscience, 2012 - Soc Neuroscience
Balance in the body9s hormonal axes depends on feedback onto neuroendocrine
hypothalamic neurons. This phenomenon involves transcriptional and biosynthetic effects …

Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice

PR Le Tissier, DJ Hodson, AO Martin… - Recent Advances in …, 2015 - Springer
The output of prolactin (PRL) is highly dynamic with dramatic changes in its secretion from
the anterior pituitary gland depending on prevailing physiological status. In adult female …

Excitation of tuberoinfundibular dopamine neurons by oxytocin: crosstalk in the control of lactation

V Briffaud, P Williams, J Courty… - Journal of …, 2015 - Soc Neuroscience
Milk production in the nursing mother is induced by the hormone prolactin. Its release from
the anterior pituitary is generally under tonic inhibition by neuroendocrine tuberoinfundibular …

Conditional deletion of the prolactin receptor reveals functional subpopulations of dopamine neurons in the arcuate nucleus of the hypothalamus

RSE Brown, IC Kokay, HR Phillipps, SH Yip… - Journal of …, 2016 - Soc Neuroscience
Tuberoinfundibular dopamine (TIDA) neurons, known as neuroendocrine regulators of
prolactin secretion from the pituitary gland, also release GABA within the hypothalamic …

Dephosphorylation/inactivation of tyrosine hydroxylase at the median eminence of the hypothalamus is required for suckling-induced prolactin and adrenocorticotrop …

P Fehér, M Oláh, I Bodnár, D Hechtl, I Bácskay… - Brain research …, 2010 - Elsevier
We have recently found that dopamine (DA) released from terminals of the hypothalamic
neuroendocrine dopamine (NEDA) neurons plays a role not only in prolactin (PRL), but also …

Differential actions of prolactin on electrical activity and intracellular signal transduction in hypothalamic neurons

RSE Brown, R Piet, AE Herbison, DR Grattan - Endocrinology, 2012 - academic.oup.com
In many tissues, including brain, prolactin action is predominantly mediated by the Janus
kinase/signal transducer and activator of transcription (STAT) signal transduction pathway …