Changes in the local metabolism of dopamine in the anterior and neural lobes but not in the intermediate lobe of the pituitary gland during nursing

GM Nagy, JE DeMaria, ME Freeman - Brain research, 1998 - Elsevier
Dopamine (DA), produced by tubero-infundibular dopaminergic (TIDA) neurons of the
arcuate nucleus (ARN) is the established inhibitor of the secretion of prolactin (PRL) …

Mechanisms underlying the diminished sensitivity to prolactin negative feedback during lactation: reduced STAT5 signaling and up-regulation of cytokine-inducible …

ST Anderson, JL Barclay, KJ Fanning… - …, 2006 - academic.oup.com
Hyperprolactinaemia during lactation is a consequence of the sucking stimulus and in part
due to reduced prolactin (PRL) negative feedback. To date, the mechanisms involved in this …

Estrogen inhibits tuberoinfundibular dopaminergic neurons but does not cause irreversible damage

GR Morel, RW Carón, GM Cónsole, M Soaje… - Brain research …, 2009 - Elsevier
Dopaminergic neurons of the hypothalamic tuberoinfundibular dopaminergic (TIDA) system
exert a tonic inhibitory control on prolactin (PRL) secretion whereas estrogen, known to …

Differential changes in the hypothalamic‐pituitary‐adrenal axis and prolactin responses to stress in early pregnant mice

VJ Parker, JRW Menzies… - Journal of …, 2011 - Wiley Online Library
Stress can cause pregnancy failure but it is unclear how the mother's neuroendocrine
system responds to stress to impair mechanisms establishing implantation. We analysed …

Feedback effects of placental lactogens on prolactin levels and Fos-related antigen immunoreactivity of tuberoinfundibular dopaminergic neurons in the arcuate …

Y Lee, JL Voogt - Endocrinology, 1999 - academic.oup.com
PRL in the rat exerts its luteotropic action during the first half of pregnancy. After
midpregnancy, placental lactogens (PLs) take the place of PRL to stimulate progesterone …

Low concentrations of dopamine increase cytosolic calcium in lactotrophs

TP Burris, ME Freeman - Endocrinology, 1993 - academic.oup.com
Dopamine (DA) plays a dual role in the neuroendocrine regulation of PRL secretion from the
anterior pituitary gland. DA normally exerts a tonic inhibitory effect on PRL secretion …

Involvement of hypothalamic dopamine in the regulation of prolactin secretion

MJ Reymond, JC Porter - Hormone Research in Paediatrics, 1985 - karger.com
The neuroendocrine control of prolactin (PRL) secretion is known to be a multifactorial
process, but dopamine (DA) secreted by the tuberoinfundibular dopaminergic (TIDA) …

Effects of prolactin on hypothalamic supraoptic neurones: evidence for modulation of STAT5 expression and electrical activity.

J Townsend, BJ Cave, MR Norman, A Flynn… - Neuro endocrinology …, 2005 - europepmc.org
Objectives The study investigated the role of prolactin (PRL) in modulating STAT5 and
electrical activity of magnocellular neurones in the supraoptic (SO) nucleus of male rats …

Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse

T Georgescu, SR Ladyman, RSE Brown… - Journal of …, 2020 - Wiley Online Library
In addition to its critical role in lactation, the anterior pituitary hormone prolactin also
influences a broad range of other physiological processes. In particular, widespread …

Assessment of lactotroph axis functionality in mice: longitudinal monitoring of PRL secretion by ultrasensitive-ELISA

A Guillou, N Romano, F Steyn, K Abitbol… - …, 2015 - academic.oup.com
The pattern of prolactin (PRL) secretion depends on the physiological state. Due to
insufficient detection sensitivity of existing assays, the precise description of these patterns …