To examine the regulation of midbrain dopamine neurons, recordings were obtained from
single neurons of freely moving, genetically engineered dopamine-deficient (DD) mice. DD …

There are several distinct populations of dopamine neurones in the hypothalamus. Some of
these, such as the A12 tuberoinfundibular dopamine neurones and the A14 periventricular …

The hypothalamic neuroendocrine dopaminergic (NEDA) neurons are crucial in regulating
prolactin secretion from the anterior pituitary. Rising prolactin concentrations stimulate these …

Prolactin is an anterior pituitary hormone critical for maintaining pregnancy and lactation.
Under normal conditions, prolactin secretion is tightly regulated by inhibitory dopaminergic …

During lactation, there are numerous functional adaptations in the maternal brain. There is
evidence that the high levels of circulating prolactin present during lactation might contribute …

Dopamine (DA) is the major physiological regulator of prolactin secretion from the anterior
pituitary, exerting a tonic inhibitory control that is mediated by D2 DA receptors. D2 receptors …

In this study, the dopamine turnover in the mediobasal hypothalamus, the key compartment
of the neuroendocrine regulation of reproduction, was evaluated in fetal male and female …

During the first half of pregnancy rats exhibit a diurnal-nocturnal pattern of
tuberoinfundibular dopaminergic (TIDA) neuronal activity, which is directly out of phase with …

Hypothalamic dopamine inhibits pituitary prolactin secretion and proliferation of prolactin-
producing lactotroph cells by activating lactotroph dopamine D2 receptors (D2Rs) …

Dopamine D2 receptors signal through the pertussis toxin (PTX)-sensitive Gi/o and PTX-
insensitive Gz proteins, as well as through a G protein-independent, β-arrestin/glycogen …