Therapeutic approaches to amyotrophic lateral sclerosis from the lab to the clinic
Amyotrophic Lateral Sclerosis (ALS) is a terminal neuro-degenerative disorder that is
clinically recognized as a gradual degeneration of the upper and lower motor neurons, with …
clinically recognized as a gradual degeneration of the upper and lower motor neurons, with …
Current developments in gene therapy for amyotrophic lateral sclerosis
JM Scarrott, S Herranz-Martín, AR Alrafiah… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is a devastating adult neurodegenerative
disorder characterized by motor neuron degeneration and death around 3 years from onset …
disorder characterized by motor neuron degeneration and death around 3 years from onset …
Roots to start research in amyotrophic lateral sclerosis: molecular pathways and novel therapeutics for future
D Harikrishnareddy, S Misra, S Upadhyay… - Reviews in the …, 2015 - degruyter.com
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
[HTML][HTML] Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
LM Gittings, R Sattler - Faculty reviews, 2020 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is
characterized by degeneration of both upper and lower motor neurons and subsequent …
characterized by degeneration of both upper and lower motor neurons and subsequent …
New therapeutic targets for amyotrophic lateral sclerosis
M Kuzma-Kozakiewicz, H Kwiecinski - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
disorders, affecting approximately half a million people worldwide. Currently there is no cure …
Translational Therapeutic Str ategies in Amyotrophic Lateral Sclerosis
H Ryu, RJ Ferrante - Mini Reviews in Medicinal Chemistry, 2007 - ingentaconnect.com
Amyotrophic lateral sclerosis (ALS) is a clinically severe and fatal neurodegenerative
disease characterized by a loss of both upper and lower motor neurons, resulting in …
disease characterized by a loss of both upper and lower motor neurons, resulting in …
Gene therapy for amyotrophic lateral sclerosis
T Federici, NM Boulis - Neurobiology of disease, 2012 - Elsevier
Gene therapy continues to be a potential option for amyotrophic lateral sclerosis (ALS). This
chapter will inform the reader about promising therapeutic transgenes and proof-of-principle …
chapter will inform the reader about promising therapeutic transgenes and proof-of-principle …
Recent advances in amyotrophic lateral sclerosis research: perspectives for personalized clinical application
Abstract Treatment of amyotrophic lateral sclerosis (ALS) has been fueled, in part, by
frustration over the shortcomings of the symptomatic drugs available, since these do not …
frustration over the shortcomings of the symptomatic drugs available, since these do not …
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …
Biomarkers and future targets for development in amyotrophic lateral sclerosis
Although the pathophysiological mechanisms underlying the development of amyotrophic
lateral sclerosis (ALS) remain to be fully elucidated, there have been significant advances in …
lateral sclerosis (ALS) remain to be fully elucidated, there have been significant advances in …