Probabilistic mapping of the antidystonic effect of pallidal neurostimulation: a multicentre imaging study

MM Reich, A Horn, F Lange, J Roothans, S Paschen… - Brain, 2019 - academic.oup.com
Deep brain stimulation of the internal globus pallidus is a highly effective and established
therapy for primary generalized and cervical dystonia, but therapeutic success is …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li… - Proceedings of the …, 2022 - National Acad Sciences
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

Deep brain stimulation for dystonia

M Vidailhet, MF Jutras, E Roze, D Grabli - Handbook of clinical neurology, 2013 - Elsevier
The few reported controlled studies show that bilateral stimulation of the globus pallidus
interna (GPi) is a safe and effective long-term treatment for hyperkinetic disorders. However …

Pallidal deep brain stimulation in patients with primary generalised or segmental dystonia: 5-year follow-up of a randomised trial

J Volkmann, A Wolters, A Kupsch, J Müller… - The Lancet …, 2012 - thelancet.com
Background Severe forms of primary dystonia are difficult to manage medically. We
assessed the safety and efficacy of pallidal neurostimulation in patients with primary …

Functional and structural connectivity patterns associated with clinical outcomes in deep brain stimulation of the globus pallidus internus for generalized dystonia

L Okromelidze, T Tsuboi, RS Eisinger… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Deep brain stimulation is a well-established treatment for
generalized dystonia, but outcomes remain variable. Establishment of an imaging marker to …

[HTML][HTML] Pallidal deep-brain stimulation in primary generalized or segmental dystonia

A Kupsch, R Benecke, J Müller… - … England Journal of …, 2006 - Mass Medical Soc
Background Neurostimulation of the internal globus pallidus has been shown to be effective
in reducing symptoms of primary dystonia. We compared this surgical treatment with sham …

Deep brain stimulation in dystonia

A Kupsch, A Kuehn, S Klaffke, W Meissner… - Journal of …, 2003 - Springer
Renewed interest in stereotaxy for dystonia followed the introduction of deep brain
stimulation (DBS) in Parkinson's disease and essential tremor in the 1990s. DBS evolved …

[HTML][HTML] Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes

PA Starr, RS Turner, G Rau, N Lindsey, S Heath… - Neurosurgical …, 2004 - thejns.org
Object Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a promising new
procedure for the treatment of dystonia. The authors present their technical approach for …

Efficacy of pallidal stimulation in isolated dystonia: a systematic review and meta‐analysis

E Moro, C LeReun, JK Krauss… - European journal of …, 2017 - Wiley Online Library
The aim of this review was to provide strong clinical evidence of the efficacy of deep brain
stimulation (DBS) of the globus pallidus internus (GPi) in isolated inherited or idiopathic …

Long-term effects of pallidal deep brain stimulation in tardive dystonia

D Gruber, T Trottenberg, A Kivi, T Schoenecker… - Neurology, 2009 - AAN Enterprises
Objective: High-frequency stimulation of the globus pallidus internus (GPi) is a highly
effective therapy in primary dystonia. Recent reports have also demonstrated almost …