Sleep disturbance: an early sign of Alzheimer's disease
C He, Z Hu, C Jiang - Neuroscience Bulletin, 2020 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
cognitive impairment in older adults. The accumulation of insoluble forms of amyloid-b (Ab) …
cognitive impairment in older adults. The accumulation of insoluble forms of amyloid-b (Ab) …
[HTML][HTML] Sleep in Alzheimer's disease–beyond amyloid
JK Holth, TK Patel, DM Holtzman - Neurobiology of sleep and circadian …, 2017 - Elsevier
Sleep disorders are prevalent in Alzheimer's disease (AD) and a major cause of
institutionalization. Like AD pathology, sleep abnormalities can appear years before …
institutionalization. Like AD pathology, sleep abnormalities can appear years before …
[HTML][HTML] Mounting Evidence on the Relationship between Sleep and Alzheimer's Disease
L De Gennaro, S Cordone - Journal of Integrative Neuroscience, 2024 - imrpress.com
The relationship between sleep and Alzheimer's disease (AD) has become increasingly
apparent in recent years with the results of new scientific investigations and with AD being …
apparent in recent years with the results of new scientific investigations and with AD being …
Sleep and Alzheimer disease pathology—a bidirectional relationship
Factors other than age and genetics may increase the risk of developing Alzheimer disease
(AD). Accumulation of the amyloid-β (Aβ) peptide in the brain seems to initiate a cascade of …
(AD). Accumulation of the amyloid-β (Aβ) peptide in the brain seems to initiate a cascade of …
[HTML][HTML] Sleep disorders associated with Alzheimer's disease: a perspective
Sleep disturbances, as well as sleep-wake rhythm disturbances, are typical symptoms of
Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative …
Alzheimer's disease (AD) that may precede the other clinical signs of this neurodegenerative …
Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors
C Wang, DM Holtzman - Neuropsychopharmacology, 2020 - nature.com
As we age, we experience changes in our nighttime sleep and daytime wakefulness.
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …
Sleep disturbances in Alzheimer's and Parkinson's diseases
SM Rothman, MP Mattson - Neuromolecular medicine, 2012 - Springer
Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurodegenerative disorders and exact a burden on our society greater than cardiovascular …
neurodegenerative disorders and exact a burden on our society greater than cardiovascular …
[HTML][HTML] It's complicated: The relationship between sleep and Alzheimer's disease in humans
BP Lucey - Neurobiology of disease, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an
asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque …
asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque …
The sleep–wake cycle and Alzheimer's disease: what do we know?
Sleep–wake disturbances are a highly prevalent and often disabling feature of Alzheimer's
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …
disease (AD). A cardinal feature of AD includes the formation of amyloid plaques, associated …
Beyond the sleep-amyloid interactions in Alzheimer's disease pathogenesis
Cognitive impairment in older adults is associated with sleep and circadian rhythm
disturbances. Numerous studies have linked disrupted sleep and circadian rhythms with …
disturbances. Numerous studies have linked disrupted sleep and circadian rhythms with …