Sleep deficits in mild cognitive impairment are related to increased levels of plasma amyloid-β and cortical thinning

MP Sanchez-Espinosa, M Atienza, JL Cantero - Neuroimage, 2014 - Elsevier
Evidence suggests that amyloid-beta (Aβ) depositions parallel sleep deficits in Alzheimer's
disease (AD). However, it remains unknown whether impaired sleep and changes in plasma …

[HTML][HTML] Sleep and Alzheimer: the link

G Archana, A Kaliappan, Y Balan, V Sakthivadivel… - Maedica, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease is the most common type of dementia which has both cognitive and non-
cognitive disabilities. Recent research has proved that sleep deprivation and insomnia have …

Decoding the Inter-Relationship between sleep disorders and Alzheimer's disease pathogenesis

Z Mueed, PK Rai, MA Kamal… - CNS & Neurological …, 2021 - ingentaconnect.com
Alzheimer's Disease (AD), characterized by abnormally phosphorylated tau, Paired Helical
Filaments (PHFs), Neurofibrillary Tangles (NFTs), deregulated mammalian Target Of …

Sleep and β-amyloid deposition in Alzheimer disease: insights on mechanisms and possible innovative treatments

S Cordone, L Annarumma, PM Rossini… - Frontiers in …, 2019 - frontiersin.org
The growing interest in the preclinical stage of Alzheimer's disease (AD) led investigators to
identify modifiable risk and predictive factors useful to design early intervention strategies …

Sleep in Alzheimer's disease: a systematic review and meta-analysis of polysomnographic findings

Y Zhang, R Ren, L Yang, H Zhang, Y Shi… - Translational …, 2022 - nature.com
Polysomnography (PSG) studies of sleep changes in Alzheimer's disease (AD) have
reported but not fully established the relationship between sleep disturbances and AD. To …

Exploring the bi-directional relationship between sleep and beta-amyloid

BM Brown, SR Rainey-Smith, RS Bucks… - Current opinion in …, 2016 - journals.lww.com
Recent findings indicate that poor sleep is a risk factor for brain Aβ deposition, and Aβ
deposition contributes to sleep disruption. Through the conduct of more mechanistic studies …

Sleep disturbance as a potential modifiable risk factor for Alzheimer's disease

EN Minakawa, K Wada, Y Nagai - International journal of molecular …, 2019 - mdpi.com
Sleep disturbance is a common symptom in patients with various neurodegenerative
diseases, including Alzheimer's disease (AD), and it can manifest in the early stages of the …

Age associated sleep loss: a trigger for Alzheimer's disease

VK Sharma, P Sharma, R Deshmukh… - … Bülteni-Bulletin of …, 2015 - Taylor & Francis
Alzheimer's disease (AD) is an untreatable, multifactorial, chronic, progressive,
neurodegenerative disorder, which is the principal cause of dementia throughout the world …

Disturbed sleep in preclinical cognitive impairment: cause and effect?

BA Mander - Sleep, 2013 - academic.oup.com
Cognitive decline in old age, particularly impairments associated with neurodegenerative
dementias such as Alzheimer disease (AD), represents one of the largest public health and …

Sleep disturbance: an emerging opportunity for Alzheimer's disease prevention?

AP Spira, RF Gottesman - International psychogeriatrics, 2017 - cambridge.org
As the older segment of our population grows, cognitive decline and dementia will increase
in prevalence, with Alzheimer's disease (AD) as the cause in most cases. Until a cure exists …