Clinical and pharmacological implications of time to treatment with interleukin-1 blockade in ST-segment elevation myocardial infarction
Interleukin-1 (IL-1) blockade with anakinra given within 12 hours from reperfusion has been
shown to reduce the inflammatory response as well as prevent heart failure (HF) events in …
shown to reduce the inflammatory response as well as prevent heart failure (HF) events in …
Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot …
A Abbate, MC Kontos, NA Abouzaki… - The American journal of …, 2015 - Elsevier
Two pilot studies of interleukin-1 (IL-1) blockade in ST-segment elevation myocardial
infarction (STEMI) showed blunted acute inflammatory response and overall favorable …
infarction (STEMI) showed blunted acute inflammatory response and overall favorable …
Interleukin‐1 blockade inhibits the acute inflammatory response in patients with ST‐segment–elevation myocardial infarction
Background ST‐segment–elevation myocardial infarction is associated with an intense
acute inflammatory response and risk of heart failure. We tested whether interleukin‐1 …
acute inflammatory response and risk of heart failure. We tested whether interleukin‐1 …
Interleukin-1 blockade with anakinra and heart failure following ST-segment elevation myocardial infarction: results from a pooled analysis of the VCUART clinical …
Aims ST-segment elevation myocardial infarction (STEMI) is associated with an intense
acute inflammatory response and an increased risk of death and heart failure (HF). In this …
acute inflammatory response and an increased risk of death and heart failure (HF). In this …
Effect of interleukin-1 blockade with anakinra on leukocyte count in patients with ST-segment elevation acute myocardial infarction
Leukocytosis is a common finding in patients with ST elevation myocardial infarction
(STEMI) and portends a poor prognosis. Interleukin 1-β regulates leukopoiesis and pre …
(STEMI) and portends a poor prognosis. Interleukin 1-β regulates leukopoiesis and pre …
Response to interleukin-1 blockade with anakinra in women and men with ST-segment elevation myocardial infarction
G Corna, M Golino, AH Talasaz… - Minerva cardiology …, 2024 - pubmed.ncbi.nlm.nih.gov
Background Interleukin-1 blockade with anakinra reduces high-sensitivity C-reactive protein
(hsCRP) levels and prevents heart failure (HF) events after ST-segment myocardial …
(hsCRP) levels and prevents heart failure (HF) events after ST-segment myocardial …
Impact of C-reactive protein levels and role of anakinra in patients with ST-elevation myocardial infarction
Background Interleukin-1 blockade with anakinra reduces C-reactive protein (CRP) levels
and prevents heart failure (HF) events after ST-segment myocardial infarction (STEMI). The …
and prevents heart failure (HF) events after ST-segment myocardial infarction (STEMI). The …
Rationale and design of the Virginia Commonwealth University–Anakinra Remodeling Trial‐3 (VCU‐ART3): A randomized, placebo‐controlled, double‐blinded …
BW Van Tassell, MJ Lipinski, D Appleton… - Clinical …, 2018 - Wiley Online Library
There is clear association between the intensity of the acute inflammatory response during
acute myocardial infarction (AMI) and adverse prognosis after AMI. Interleukin‐1 (IL‐1) is a …
acute myocardial infarction (AMI) and adverse prognosis after AMI. Interleukin‐1 (IL‐1) is a …
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra …
A Abbate, MC Kontos, JD Grizzard… - The American journal of …, 2010 - Elsevier
Acute myocardial infarction (AMI) initiates an intense inflammatory response in which
interleukin-1 (IL-1) plays a central role. The IL-1 receptor antagonist is a naturally occurring …
interleukin-1 (IL-1) plays a central role. The IL-1 receptor antagonist is a naturally occurring …
[HTML][HTML] Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia commonwealth university anakinra …
A Abbate, MC Kontos, JD Grizzard… - The American journal …, 2013 - ncbi.nlm.nih.gov
Acute myocardial infarction (AMI) initiates an intense inflammatory response in which
interleukin-1 (IL-1) plays a central role. The IL-1 receptor antagonist is a naturally occurring …
interleukin-1 (IL-1) plays a central role. The IL-1 receptor antagonist is a naturally occurring …