Abstract Knowledge of therapeutic targets and early drug candidates is useful for improved
drug discovery. In particular, information about target regulators and the patented …

Extensive efforts have been directed at the discovery, investigation and clinical monitoring of
targeted therapeutics. These efforts may be facilitated by the convenient access of the …

Extensive drug discovery efforts have yielded many approved and candidate drugs targeting
various targets in different biological pathways. Several freely accessible databases provide …

A number of proteins and nucleic acids have been explored as therapeutic targets. These
targets are subjects of interest in different areas of biomedical and pharmaceutical research …

Increasing numbers of proteins, nucleic acids and other molecular entities have been
explored as therapeutic targets, hundreds of which are targets of approved and clinical trial …

Here we describe an update of the Therapeutic Target Database (http://bidd. nus. edu.
sg/group/ttd/ttd. asp) for better serving the bench-to-clinic communities and for enabling …

Drug discovery relies on the knowledge of not only drugs and targets, but also the
comparative agents and targets. These include poor binders and non-binders for developing …

With the rapid accumulation of our knowledge on diseases, disease-related genes and drug
targets, network-based analysis plays an increasingly important role in systems biology …

Abstract Knowledge and investigation of therapeutic targets (responsible for drug efficacy)
and the targeted drugs facilitate target and drug discovery and validation. Therapeutic …

Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …