Immune pathogenesis of diabetes in the nonobese diabetic mouse: an overview
T Hanafusa, S Tarui - The Role of Viruses and the Immune System in …, 1990 - Springer
A considerable amount of evidence suggests that human type 1 or insulin-dependent
diabetes mellitus (IDDM) is a chronic autoimmune disease with a long preclinical period. It is …
diabetes mellitus (IDDM) is a chronic autoimmune disease with a long preclinical period. It is …
The BioBreeding rat diabetes model is infected with Ljungan virus
B Niklasson, T Hultman, R Kallies, M Niedrig, R Nilsson… - Diabetologia, 2007 - Springer
To the Editor: A useful tool for understanding the pathogenesis of human diseases has been
the use of animal models. The BioBreeding (BB) rat has been a useful source of knowledge …
the use of animal models. The BioBreeding (BB) rat has been a useful source of knowledge …
[HTML][HTML] Viral trigger for type 1 diabetes: pros and cons
CM Filippi, MG von Herrath - Diabetes, 2008 - ncbi.nlm.nih.gov
The most popular hypothesis circulating within and beyond the scientific community is that
viral infections enhance or elicit autoimmune disorders such as type 1 diabetes. Indeed …
viral infections enhance or elicit autoimmune disorders such as type 1 diabetes. Indeed …
The viral paradigm in type 1 diabetes: who are the main suspects?
T Rodriguez-Calvo, S Sabouri, F Anquetil… - Autoimmunity …, 2016 - Elsevier
Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by the loss of
pancreatic beta cells in the islets of Langerhans. Although genetic predisposition plays an …
pancreatic beta cells in the islets of Langerhans. Although genetic predisposition plays an …
Maternal environment affects endogenous virus induction in the offspring of type 1 diabetes model non‐obese diabetic mice
Y Kagohashi, J Udagawa, K Moriyama… - Congenital …, 2005 - Wiley Online Library
Type 1 diabetes results from the destruction of pancreatic b‐cells (insulitis). It is a
multifactorial disease involving genetic and environmental factors, including the maternal …
multifactorial disease involving genetic and environmental factors, including the maternal …
Can we learn from viruses how to prevent type 1 diabetes? The role of viral infections in the pathogenesis of type 1 diabetes and the development of novel …
M von Herrath - Diabetes, 2009 - Am Diabetes Assoc
We will take a journey from basic pathogenetic mechanisms elicited by viral infections that
play a role in the development of type 1 diabetes to clinical interventions, where we will …
play a role in the development of type 1 diabetes to clinical interventions, where we will …
Effectiveness of antivirals in A type 1 diabetes model and the move toward human trials
B Niklasson, W Klitz, L Juntti-Berggren… - Viral …, 2020 - liebertpub.com
A Picornavirus (Ljungan virus [LV]) originally found in bank voles has been associated with
type 1 diabetes (T1D) in its wild rodent reservoir, but also associated with T1D in a …
type 1 diabetes (T1D) in its wild rodent reservoir, but also associated with T1D in a …
Diabetes prevention through antiviral treatment in biobreeding rats
B Niklasson, G Arbrandt, A Kawecki… - Viral …, 2016 - liebertpub.com
A picornavirus (Ljungan virus) has been associated with diabetes in its wild rodent reservoir
and in diabetes-prone biobreeding (DP-BB) rats. We attempted to alter the development of …
and in diabetes-prone biobreeding (DP-BB) rats. We attempted to alter the development of …
Rodent models for diabetes
Diabetes mellitus (DM) is associated with many health complications and is potentially a
morbid condition. As prevalence increases at an alarming rate around the world, research …
morbid condition. As prevalence increases at an alarming rate around the world, research …