BACKGROUND Currently used prognostic markers are limited in their ability to accurately
predict disease progression among patients with localized prostate cancer. We examined 23 …

Genome-wide association studies (GWAS) have resulted in the identification of numerous
single-nucleotide polymorphisms (SNPs) that are associated with prostate cancer (PCa) …

Previous studies have indicated that hereditary prostate cancer is common among men with
early onset prostate cancer. The aim of this study was to investigate the incidence of …

Importance Few studies have evaluated the association between a single-nucleotide
polymorphism–based genetic risk score (GRS) and patient age at prostate cancer (PCa) …

Prostate cancer (PCa) is one of the most common cancers among men in Western
developed countries and its incidence has increased considerably in many other parts of the …

BACKGROUND Prostate cancer (PCa) risk‐associated single‐nucleotide polymorphisms
(SNPs) are continuously being discovered. Their ability to identify men at high risk and the …

e16548 Background: Family history (FH) is a well-documented risk factor for prostate cancer
(PCa). Previously, germline pathogenic variants (PVs) have been identified in metastatic …

Decreasing costs of genetic testing and interest in disease inheritance has changed the
landscape of cancer prediction in prostate cancer (PCa), and guidelines now include …

Polygenic risk scores (PRSs) for a variety of diseases have recently been shown to have
relative risks that depend on age, and genetic relative risks decrease with increasing age. A …