Antihypertensive treatment during pregnancy induces long-term changes in gut microbiota and the behaviors of the attention deficit hyperactivity disorder offspring
HB Li, ML Xu, WJ Xia, YY Dong, B Peng, Q Su… - Toxicology and Applied …, 2024 - Elsevier
The pathogenesis of attention-deficit/hyperactivity disorder (ADHD) has not been fully
elucidated. Gestational hypertension could double the probability of ADHD in the offspring …
elucidated. Gestational hypertension could double the probability of ADHD in the offspring …
Maternal treatment with captopril persistently alters gut-brain communication and attenuates hypertension of male offspring
HB Li, T Yang, EM Richards, CJ Pepine… - Hypertension, 2020 - Am Heart Assoc
Maternal-fetal crosstalk has been implicated in long-term control of the health of offspring,
including transgenerational hypertension. However, current knowledge is limited regarding …
including transgenerational hypertension. However, current knowledge is limited regarding …
[HTML][HTML] A novel role for maternal stress and microbial transmission in early life programming and neurodevelopment
E Jašarević, AB Rodgers, TL Bale - Neurobiology of stress, 2015 - Elsevier
Perturbations in the prenatal and early life environment can contribute to the development of
offspring stress dysregulation, a pervasive symptom in neuropsychiatric disease …
offspring stress dysregulation, a pervasive symptom in neuropsychiatric disease …
[HTML][HTML] Maternal pre-pregnancy and prenatal penicillin, neonatal inflammation and growth factors are associated to ADHD in the offspring
S Holmgaard, P Kiilerich, N Borbye-Lorenzen… - Brain, Behavior, & …, 2024 - Elsevier
Abstract Background The etiology for Attention Deficit Hyperactivity Disorder (ADHD) is
generally unknown, but both genetics, biology and environment have been shown to …
generally unknown, but both genetics, biology and environment have been shown to …
Gestational stress and perinatal SSRIs differentially impact the maternal and neonatal microbiome‐gut‐brain axis
JL Pawluski, P Murail, F Grudet, L Bys… - Journal of …, 2023 - Wiley Online Library
Selective serotonin reuptake inhibitors (SSRIs) are the most popular antidepressant
medications used to manage perinatal mood disturbances, yet our understanding of how …
medications used to manage perinatal mood disturbances, yet our understanding of how …
Association between prenatal antimicrobial use and offspring attention deficit hyperactivity disorder
JK Straughen, AR Sitarik, G Wegienka… - Plos one, 2023 - journals.plos.org
Background Gut-brain cross-talk may play an important role in modulating
neurodevelopment. Few studies have examined the association between antimicrobials that …
neurodevelopment. Few studies have examined the association between antimicrobials that …
Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring
In utero and early neonatal exposure to maternal stress is linked with psychiatric disorders,
and the underlying mechanisms are currently being elucidated. We used a prenatal stressor …
and the underlying mechanisms are currently being elucidated. We used a prenatal stressor …
Prenatal stress affects placental cytokines and neurotrophins, commensal microbes, and anxiety-like behavior in adult female offspring
TL Gur, L Shay, AV Palkar, S Fisher, VA Varaljay… - Brain, behavior, and …, 2017 - Elsevier
Recent studies demonstrate that exposure to stress changes the composition of the
intestinal microbiota, which is associated with development of stress-induced changes to …
intestinal microbiota, which is associated with development of stress-induced changes to …
[HTML][HTML] Pre-and postnatal antibiotic exposure and risk of developing attention deficit hyperactivity disorder–A systematic review and meta-analysis combining …
K Otten, L Keller, AA Puiu, B Herpertz-Dahlmann… - Neuroscience & …, 2022 - Elsevier
This study investigated the effects of early antibiotic exposure on ADHD risk by (1)
integrating meta-analytical evidence from human observational studies examining the …
integrating meta-analytical evidence from human observational studies examining the …
Perturbation of maternal gut microbiota in mice during a critical perinatal window influences early neurobehavioral outcomes in offspring
C Morel, IM Sanchez, Y Cherifi, N Chartrel… - Neuropharmacology, 2023 - Elsevier
The gut microbiota is increasingly recognized as a key environmental factor that shapes host
development and physiology, including neural circuits formation and function. Concurrently …
development and physiology, including neural circuits formation and function. Concurrently …