Besides mediating hemostatic functions, platelets are increasingly recognized as important
players of inflammation. Data from experiments in mice and men revealed various …

In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

The paradigm of platelets as mere mediators of hemostasis has long since been replaced by
a dual role: hemostasis and inflammation. Now recognized as key players in innate and …

Platelets play central roles for maintaining the homeostasis of the blood coagulation. As they
are also involved in immune responses and host defenses, increasing evidences have …

Platelets are chief effector cells in hemostasis. In addition, they are multifaceted
inflammatory cells with functions that span the continuum from innate immune responses to …

Beyond their role in hemostasis and thrombosis, platelets are increasingly recognized as
key regulators of the inflammatory response under sterile and infectious conditions. Both …

In addition to their well-described hemostatic function, platelets are active participants in
innate and adaptive immunity. Inflammation and immunity are closely related to changes in …

Thrombosis and cardiovascular complications are common manifestations of a variety of
pathological conditions, including infections and chronic inflammatory diseases. Hence …

Platelets are anucleate blood cells, long known to be critically involved in hemostasis and
thrombosis. In addition to their role in blood clots, increasing evidence reveals significant …

New findings highlight the complex interplay of innate immunity, coagulation and platelets in
inflammation and infection, and unravel novel molecular pathways and effector functions …