Neutrophil-platelet interactions as novel treatment targets in cardiovascular disease
Neutrophils and platelets are among the most abundant cell types in peripheral blood and
characterized by high plasticity and a readily available reservoir of surface proteins and …
characterized by high plasticity and a readily available reservoir of surface proteins and …
Platelet-mediated modulation of adaptive immunity
M Iannacone - Seminars in immunology, 2016 - Elsevier
Besides being the main cellular effectors of hemostasis, platelets possess a plethora of
intracellular mediators (eg cytokines, chemokines and antimicrobial molecules) as well as …
intracellular mediators (eg cytokines, chemokines and antimicrobial molecules) as well as …
Immunothrombosis and thromboinflammation in host defense and disease
K Martinod, C Deppermann - Platelets, 2021 - Taylor & Francis
Platelets are increasingly being recognized for playing roles beyond thrombosis and
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …
Platelets as immune-sensing cells
Platelets have classically been well recognized for their crucial role in hemostasis; however,
it is increasingly evident that platelets are more versatile than originally thought because …
it is increasingly evident that platelets are more versatile than originally thought because …
Platelets in host defense: experimental and clinical insights
Platelets are central players in thrombosis and hemostasis but are increasingly recognized
as key components of the immune system. They shape ensuing immune responses by …
as key components of the immune system. They shape ensuing immune responses by …
Platelets and vascular integrity: how platelets prevent bleeding in inflammation
B Ho-Tin-Noé, Y Boulaftali… - Blood, The Journal of the …, 2018 - ashpublications.org
Platelets play a central role in primary hemostasis by forming aggregates that plug holes in
injured vessels. Half a century ago, detailed studies of the microvasculature by electron …
injured vessels. Half a century ago, detailed studies of the microvasculature by electron …
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration
N Cloutier, I Allaeys, G Marcoux… - Proceedings of the …, 2018 - National Acad Sciences
There is a growing appreciation for the contribution of platelets to immunity; however, our
knowledge mostly relies on platelet functions associated with vascular injury and the …
knowledge mostly relies on platelet functions associated with vascular injury and the …
Platelets at the crossroads of pro-inflammatory and resolution pathways during inflammation
N Ludwig, A Hilger, A Zarbock, J Rossaint - Cells, 2022 - mdpi.com
Platelets are among the most abundant cells in the mammalian circulation. Classical platelet
functions in hemostasis and wound healing have been intensively explored and are …
functions in hemostasis and wound healing have been intensively explored and are …
Role of platelets in detection and regulation of infection
I Portier, RA Campbell - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …
However, in recent years, platelets have gained recognition for their inflammatory functions …
Bench-to-bedside review: Platelets and active immune functions-new clues for immunopathology?
O Garraud, H Hamzeh-Cognasse, B Pozzetto… - Critical care, 2013 - Springer
Platelets display a number of properties besides the crucial function of repairing damaged
vascular endothelium and stopping bleeding; these are exploited to benefit patients …
vascular endothelium and stopping bleeding; these are exploited to benefit patients …