Analytic performance of immunoassays for drugs of abuse below established cutoff values

VI Luzzi, AN Saunders, JW Koenig, J Turk… - Clinical …, 2004 - academic.oup.com
Background: The analytic performance and accuracy of drug detection below Substance
Abuse and Mental Health Services Administration (SAMHSA) cutoffs is not well known. In …

Comparison of several immunoassays used in drugs of abuse screening: Assessment against gold standard methods and calculation of measurement uncertainty

A Mina - Journal of pharmacological and toxicological methods, 2020 - Elsevier
Background Immunoassays provide simple, powerful and inexpensive screening methods
for urine drug screening. Other substances and/or factors may interfere with the test and …

Limitations of immunoassays for screening of drugs of abuse in urine: issues of false positive and false negative results

JM Boyd, SMH Sadrzadeh - Accurate results in the clinical laboratory, 2019 - Elsevier
Urine drugs of abuse testing has screening by immunoassay is routinely used for clinical
and forensic applications. Although immunoassay screens can provide a fast result for many …

Interpretation and utility of drug of abuse screening immunoassays: insights from laboratory drug testing proficiency surveys

MD Krasowski, GA McMillin… - … of Pathology & …, 2020 - meridian.allenpress.com
Context.—Urine drug testing is frequently ordered by health care providers. Immunoassays
are widely used for drug testing, yet have potential limitations, including variable cross …

A retrospective analysis of urine drugs of abuse immunoassay true positive rates at a national reference laboratory

KL Johnson-Davis, AJ Sadler… - Journal of Analytical …, 2016 - academic.oup.com
Urine drug screens are commonly performed to identify drug use or monitor adherence to
drug therapy. The purpose of this retrospective study was to evaluate the true positive and …

Accuracy of five on-site immunoassay drugs-of-abuse testing devices

EH Taylor, EH Oertli, JW Wolfgang… - Journal of analytical …, 1999 - academic.oup.com
Many current “on-site” urine drug-testing products claim performance equivalent to
laboratory testing. Five commercially available products (PharmScreen™, Roche TestCup® …

False-negative results in the immunoassay analysis of drugs of abuse: can adulterants be detected by sample check test?

B Matriciani, B Huppertz, R Keller… - Annals of Clinical …, 2018 - journals.sagepub.com
Background The dilution or adulteration of urine is a serious problem in drugs of abuse
testing. Tests to identify adulteration are currently available. This study investigated the …

The utility of immunoassays for urine drug testing

SEF Melanson - Clinics in laboratory medicine, 2012 - Elsevier
Substance abuse is a significant problem in the United States. 1 Over 2.1 million emergency
department visits in 2009 were associated with drug misuse or abuse, of which 47 …

Positive predictive values of abused drug immunoassays on the Beckman Synchron in a veteran population

DJ Dietzen, K Ecos, D Friedman… - Journal of analytical …, 2001 - academic.oup.com
The pressure to reduce the cost of analytic testing makes it tempting to discontinue routine
confirmation of urine specimens positive for drugs of abuse by immunoassay. Beyond the …

Impact of lowering the screening and confirmation cutoff values for urine drug testing based on dilution indicators

AD Fraser, J Zamecnik - Therapeutic drug monitoring, 2003 - journals.lww.com
Many clinical and forensic toxicology laboratories establish criteria for identifying a random
urine specimen submitted for drug screening as being “normally concentrated” or “dilute” by …