Bacterial metabolism is necessary for adaptation to the host microenvironment. Flexible
metabolic pathways allow uropathogenic Escherichia coli (UPEC) to harmlessly reside in …

Bacterial growth in the host is required for pathogenesis. To successfully grow in vivo,
pathogens have adapted their metabolism to replicate in specific host microenvironments …

Escherichia coli ordinarily resides in the lower gastrointestinal tract in humans, but some
strains, known as Uropathogenic E. coli (UPEC), are also adapted to the relatively harsh …

Microbial pathogenesis studies traditionally encompass dissection of virulence properties
such as the bacterium's ability to elaborate toxins, adhere to and invade host cells, cause …

Uropathogenic Escherichia coli (UPEC) is responsible for more than 75% of urinary tract
infections (UTIs) and has been studied extensively to better understand the molecular …

In the present study, it is shown that although Escherichia coli CFT073, a human
uropathogenic (UPEC) strain, grows in liquid glucose M9 minimal medium, it fails to grow on …

The human genitourinary tract is a common anatomical niche for polymicrobial infection and
a leading site for the development of bacteremia and sepsis. Most uncomplicated …

The metabolic regulation of Escherichia coli lacking a functional pykF gene was investigated
based on gene expressions, enzyme activities, intracellular metabolite concentrations and …

Urinary tract infections (UTIs), caused primarily by uropathogenic Escherichia coli (UPEC),
are among the most common bacterial infections in humans, costing billions of dollars …

Extraintestinal Escherichia coli (E. coli) evolved by acquisition of pathogenicity islands,
phage, plasmids, and DNA segments by horizontal gene transfer. Strains are …