Renal epithelial cell tumors are composed of a heterogeneous group of tumors with variable
morphologic, immunohistochemical, and molecular features. A “histo-molecular” approach is …

Kidney and upper urinary tract cancers account for approximately 54,000 cases every year
in the United States, and represent about 3.7% of adult malignancies, with more than 13,000 …

Renal cell carcinoma in adult comprises a heterogeneous group of tumors with variable
clinical outcomes, which ranges from indolent to aggressively malignant. The application of …

Renal neoplasms exhibit a wide spectrum of molecular characteristics that are closely
associated with their diverse morphologic manifestations and clinical behaviors. A wealth of …

This review discusses the impact of molecular genetics on the diagnosis and prediction of
the prognosis for renal-cell tumors. Through the use of molecular techniques, it has become …

Renal cell carcinomas comprise a heterogeneous group of epithelial neoplasms with
diverse biologic potential and variable clinical outcomes. The application of molecular and …

Renal cell carcinoma is a group of malignancies arising from the epithelium of the renal
tubules. The pattern of somatic mutations in kidney tumors has been extensively …

Over the last decade several genetic alterations involved in the pathogenesis and
progression of renal cell carcinoma have been identified. These findings will have a wide …

Kidney cancer is a tumor comprising several histologic subtypes, the molecular hallmarks of
which support their classification as distinct entities. Whereas the vast majority of renal …

Recent developments in (molecular) genetics have led to a better understanding of renal
tumor biology. The current knowledge of the genetics of benign as well as malignant renal …