[HTML][HTML] A systematic review and meta-analysis on the efficacy of statins in the treatment of atherosclerosis

J Jia, L Zhang, L Wang, C Ji, R Xia… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: It was a meta-analysis on the efficacy of statins in the treatment of
atherosclerosis. Methods: The PubMed, Medline, Embase, Web of Sciences, and other …

[HTML][HTML] Statins for the primary prevention of coronary heart disease

M Li, X Wang, X Li, H Chen, Y Hu, X Zhang… - BioMed Research …, 2019 - hindawi.com
Object. The purpose of this study was to fully assess the role of statins in the primary
prevention of coronary heart disease (CHD). Methods. We searched six databases …

Efficacy and safety of statin treatment for cardiovascular disease: a network meta-analysis of 170 255 patients from 76 randomized trials

EJ Mills, P Wu, G Chong, I Ghement… - … Journal of Medicine, 2011 - academic.oup.com
Background: Statins represent the largest selling class of cardiovascular drug in the world.
Previous randomized trials (RCTs) have demonstrated important clinical benefits with statin …

Meta‐analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes

BMY Cheung, IJ Lauder, CP Lau… - British journal of …, 2004 - Wiley Online Library
Aims Since 2002, there have been five major outcome trials of statins reporting findings from
more than 47 000 subjects. As individual trial results differed, we performed a meta‐analysis …

Clinical outcomes in statin treatment trials: a meta-analysis

SD Ross, IE Allen, JE Connelly… - Archives of internal …, 1999 - jamanetwork.com
Objective To determine the risk of cardiovascular events and death in patients receiving
statin treatment for cholesterol regulation. Methods Systematic review and meta-analysis of …

Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials

L Smeeth, I Douglas, AJ Hall… - British journal of …, 2009 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• The effect of statins on
cardiovascular outcomes is well established.• Effects on numerous other health outcomes …

Balancing the benefits and risks of statin therapy

GB Lim - Nature Reviews Cardiology, 2016 - nature.com
“The numbers of people who avoid heart attacks and strokes by taking statin therapy are
very much larger than the numbers who have side effects with it,” claims Rory Collins, lead …

Pleiotropic effects of statins: untapped potential for statin pharmacotherapy

S Mohammad, H Nguyen, M Nguyen… - Current vascular …, 2019 - ingentaconnect.com
Background: Statins are effective for primary and secondary prevention of atherosclerotic
cardiovascular disease. They also have systemic anti-inflammatory and immunomodulating …

[HTML][HTML] Exploring new indications for statins beyond atherosclerosis: Successes and setbacks

DD Waters - Journal of Cardiology, 2010 - Elsevier
Statins have been shown to reduce cardiovascular events across a broad spectrum of
patients at risk, irrespective of baseline LDL-cholesterol levels. In a meta-analysis of 14 …

Statins: we need an independent review

F Godlee - 2016 - bmj.com
Statins are back in the news. A review published in the Lancet last week, covered in our
news story (doi: 10.1136/bmj. i4893), presents what its authors clearly consider to be a …