Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of chloroquine in dog plasma

P Singhal, A Gaur, V Behl, A Gautam… - … of Chromatography B, 2007 - Elsevier
A simple, sensitive and rapid liquid chromatography/tandem mass spectrometric (LC–
MS/MS) method was developed and validated for quantification of chloroquine, an …

HPLC method for the determination of chloroquine and its main metabolite in biological samples

P Augustijns, N Verbeke - Journal of liquid chromatography, 1990 - Taylor & Francis
An ion-pair reversed phase HPLC-method for the determination of chloroquine and
desethylchloroquine in plasma, blood and filter-paper-absorbed blood spots is described …

An improved high-performance liquid chromatographic determination of chloroquine and its major metabolite, desethylchloroquine, in human plasma

IA Yakasai - European journal of drug metabolism and …, 2006 - Springer
Samples were extracted with n-hexane and the organic layer was rejected. 10 μl aliquots of
the aqueous layer were injected onto the column. Amodiaquine was used as the internal …

Simultaneous determination of Chloroquine and its metabolite Desethyl Chloroquine in human plasma using liquid chromatography tandem mass spectrometry

C Tang, OS Sojinu - Analytical Letters, 2012 - Taylor & Francis
This study presents a liquid chromatography tandem mass spectrometry (LC-MS/MS)
method for the simultaneous determination of chloroquine (CQ) and its metabolite desethyl …

Method development and validation for rapid quantification of hydroxychloroquine in human blood using liquid chromatography–tandem mass spectrometry

LZ Wang, RYL Ong, TM Chin, WL Thuya… - … of pharmaceutical and …, 2012 - Elsevier
A novel and specific liquid chromatography–tandem mass spectrometric method (LC–
MS/MS) was developed and validated for the quantification of hydroxychloroquine in human …

Sensitive radioimmunoassay and enzyme-linked immunosorbent assay for the simultaneous determination of chloroquine and its metabolites in biological fluids

C Escande, P Chevalier, F Verdier… - Journal of pharmaceutical …, 1990 - Elsevier
Two new methods for the simultaneous determination of chloroquine and its two main
metabolites (monodesethylchloroquine and bisdesethylchloroquine) in biological samples …

Sensitive method for the determination of chloroquine and its metabolite desethyl-chloroquine in human plasma and urine by high-performance liquid chromatography

Y Bergqvist, M Frisk-Holmberg - Journal of Chromatography B: Biomedical …, 1980 - Elsevier
A method has been developed for the rapid quantitative analysis of chloroquine and its
metabolite desethyl-chloroquine in plasma, blood and urine using high-performance liquid …

Simultaneous determination of chloroquine and its three metabolites in human plasma, whole blood and urine by ion-pair high-performance liquid chromatography

P Houzé, A De Reynies, FJ Baud, MF Benatar… - … of Chromatography B …, 1992 - Elsevier
A method was developed for the separation and measurement of chloroquine and three
metabolites (desethylchloroquine, bis-desethylchloroquine and 4-amino-7-chloroquinoline) …

Simultaneous determination of chloroquine and quinine in human biological fluids by high-performance liquid chromatography

JF Chaulet, Y Robet, JM Prevosto, O Soares… - … of Chromatography B …, 1993 - Elsevier
A high-performance liquid chromatographic method with fluorescence detection is described
for the simultaneous measurement of quinine, chloroquine and mono-and …

High-performance liquid chromatographic assay for chlorquine and its two major metabolites, desethylchloroquine and bidesethylchloroquine in biological fluids

JF Chaulet, C Mounier, O Soares, JL Brazier - Analytical letters, 1991 - Taylor & Francis
A high-performance liquid chromatography (HPLC) method for the determination of
chloroquine and its two major metabolites in biological fluids is described …