There is growing evidence that oxidative stress is increased in myocardial failure and may
contribute to the structural and functional changes that lead to disease progression. The …

We investigated the effects of chronic volume overload in the absence or presence of
vitamin E supplements on the cardiac function and contractility, cardiac malondialdehyde …

Reactive oxygen species (ROS) generation has been implicated in many pathologies
including ischemia/reperfusion (I/R) injury. This led to multiple studies on antioxidant …

Background: Cardiac arrhythmias represent a significant problem globally, leading to
cerebrovascular accidents, myocardial infarction, and sudden cardiac death. There is …

Oxidative stress contributes to various cardiovascular diseases and aging and was causally
linked to the progression of heart failure (1, 2). Among the most relevant sources for reactive …

Cardiac arrhythmia occurs frequently worldwide, and in severe cases can be fatal.
Mitochondria are the power plants of cardiomyocytes. In recent studies, mitochondria under …

Objective: Xanthine oxidase (XO) inhibitors enhance myofilament Ca2+ responsiveness of
normal rat myocardium. We examined whether this inotropic action is preserved or …

Objective: Animal myocardial dysfunction induced by remote ischemia-reperfusion (IR) was
shown to be partly accomplished via a direct effect of the pro-oxidant xanthine oxidase (XO) …

The incidence of heart failure (HF) is increasing and is associated with a poor prognosis.
Moreover, HF often coexists with renal dysfunction and is associated with a worsened …

A 60-year-old woman was admitted for treatment of congestive heart failure. She had been
diagnosed with diabetes mellitus when she was 23 years old, and she began to go deaf …