As the first and rate limiting enzyme in the biosynthetic pathway for catecholamine (CA)
neurotransmitters, tyrosine hydroxylase (TH) is a specific phenotypic marker for CA cells in …

An X-gal based histochemical assay was used to detect catecholamine (CA) cells in
transgenic mouse embryos, in which the expression of the lacZ reporter was driven by the …

In vivo, neurons of the cerebral cortex of rat embryos did not stain with antibodies to the
catecholamine (CA) biosynthetic enzyme tyrosine hydroxylase (TH) even when examined …

Tyrosine hydroxylase (TH) is the rate‐limiting enzyme in the synthesis of catecholamines
and, thus, critical in determining the catecholaminergic phenotype. In this study, we have …

Tyrosine hydroxylase (TH), the first and rate-limiting enzyme in the biosynthesis of
catecholamine neurotransmitters, is expressed within central and peripheral …

We describe the transient expression of catecholaminergic traits in cranial sensory and
dorsal root ganglia of the embryonic rat in vivo. Isolated cells expressing tyrosine …

The regulation of transmitter phenotype in primary sensory neurons remains poorly
understood. However, recent studies of catecholaminergic (CA) sensory neurons suggest …

While abundant studies have begun to elucidate ontogeny of the peripheral nervous system,
molecular mechanisms underlying brain development remain obscure. To approach this …

Dopamine (DA)‐producing neurons in the ventral midbrain are generated from a specified
neuronal lineage and form selective axonal pathways that mediate multiple CNS functions …

Publisher Summary AP1 is an important element for TH gene regulation. Cis-acting
elements for tissuekell-type-specific TH gene expression are identified to be localized within …