Depleting mAbs against the pan B cell marker CD20 are remarkably effective in the
treatment of autoimmune-mediated inflammatory disorders, but the underlying mechanisms …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
is believed to have an autoimmune origin. CD4+ T cells have been well studied for their …

Background: Increasing evidence indicates a role for Epstein–Barr virus (EBV) in the
pathogenesis of multiple sclerosis (MS). EBV-infected autoreactive B cells might accumulate …

It has been noted since 1981 that late primary infection with the Epstein–Barr virus (EBV) in
adolescence or young adulthood can account for the epidemiology of multiple sclerosis …

Epidemiological studies consistently demonstrate that patients with multiple sclerosis are
almost universally infected with Epstein–Barr virus (EBV) and that the risk of developing the …

Multiple sclerosis (MS) is an inflammatory neurological disease that is widely regarded as
the outcome of complex interactions between a genetic predisposition and an environmental …

Multiple sclerosis (MS) is a disease of the central nervous system characterized by
inflammation, demyelination, and neuronal damage. Environmental and genetic factors are …

There is ongoing debate on how B cells contribute to the pathogenesis of multiple sclerosis
(MS). The success of B‐cell targeting therapies in MS highlighted the role of B cells …

Epstein-Barr virus (EBV) has been associated with multiple sclerosis (MS), however, most
studies examining the relationship between the virus and the disease have been based on …