[HTML][HTML] Significant difference in response of malignant tumor cells of individual patients to photodynamic treatment as revealed by digital holographic microscopy

AA Zhikhoreva, AV Belashov, AB Danilova… - … of Photochemistry and …, 2021 - Elsevier
The investigation of in-vitro response of cell cultures derived from tumor material of
individual patients with similar tumor localizations to photodynamic treatment is presented …

Quantitative assessment of changes in cellular morphology at photodynamic treatment in vitro by means of digital holographic microscopy

AV Belashov, AA Zhikhoreva, TN Belyaeva… - Biomedical optics …, 2019 - opg.optica.org
Temporal dependence of changes in the morphological characteristics of cells of two
cultured lines of cancer origin, HeLa and A549, induced by photodynamic treatment with …

Necrosis and apoptosis pathways of cell death at photodynamic treatment in vitro as revealed by digital holographic microscopy

IV Semenova, AV Belashov… - … , and Analysis of …, 2018 - spiedigitallibrary.org
Monitoring of variations in morphological characteristics of cultured HeLa cells after
photodynamic treatment with Radachlorin photosensitizer is performed by means of digital …

Digital holographic microscopy in label-free analysis of cultured cells' response to photodynamic treatment

AV Belashov, AA Zhikhoreva, TN Belyaeva… - Optics letters, 2016 - opg.optica.org
A methodology providing noninvasive monitoring and evaluation of the effect of
photodynamic treatment on live cells in vitro is presented. Variations in morphological …

Morphological changes in the ovarian carcinoma cells of Wistar rats induced by chemotherapy with cisplatin and dioxadet

AA Zhikhoreva, AV Belashov, VG Bespalov… - Biomedical optics …, 2018 - opg.optica.org
The development of new express methods for the analysis of the efficacy of anti-cancer
therapy on the cellular level is highly desirable for the analysis of chemotherapeutic agent …

Systemic estimation of the effect of photodynamic therapy of cancer

EA Kogan, GA Meerovich, NL Torshina… - … Therapy and Other …, 1997 - spiedigitallibrary.org
The effects of photodynamic therapy (PDT) of cancer needs objective estimation and its
unification in experimental as well as in clinical studies. They must include not only …

In vitro monitoring of photoinduced necrosis in HeLa cells using digital holographic microscopy and machine learning

AV Belashov, AA Zhikhoreva, TN Belyaeva… - JOSA A, 2020 - opg.optica.org
Digital holographic microscopy supplemented with the developed cell segmentation and
machine learning and classification algorithms is implemented for quantitative description of …

Quantification of changes in cellular morphology during cell necrosis obtained from 3D refractive index distributions

DA Gorbenko, AV Belashov, TN Belyaeva… - Journal of Physics …, 2019 - iopscience.iop.org
In this paper we perform an analysis of changes in cellular morphology in response to
photodynamic treatment in vitro. Experiments were performed by means of digital …

Digital holographic microscopy: innovative and non-destructive analysis of living cells

Z El-Schich, A Mölder, M Sebesta, L Gisselsson, K Alm… - 2010 - diva-portal.org
Abstracts of proposals for the book titled: Microscopy: Science, Technology, Applications
and Education Digital holography is a novel technique that has been developed recently to …

Evaluation of the metastatic potential of malignant cells by image processing of digital holographic microscopy data

VL Calin, M Mihailescu, EI Scarlat, AV Baluta… - FEBS Open …, 2017 - Wiley Online Library
The cell refractive index has been proposed as a putative cancer biomarker of great
potential, being correlated with cell content and morphology, cell division rate and …