Background: This 8-week, double-blind, randomized trial compared the efficacy and
tolerability of venlafaxine and sertraline in patients with major depression. Method …

We carried out a secondary analysis of a double-blind, placebo-controlled trial of
desvenlafaxine for major depressive disorder (MDD) to explore the associations between …

Objective This post hoc analysis assessed the efficacy of desvenlafaxine 50 mg/day for
treating major depressive disorder in perimenopausal versus postmenopausal women …

Importance of the field: Genetic and pharmacologically-driven variations in common
mechanisms involved in the disposition of antidepressant medications may contribute to …

Introduction: This retrospective analysis compared sensitivity to change on the 17-item and 6-
item Hamilton rating scales for depression (HAM-D 17 and HAM-D 6, respectively) in …

Background: We compared the efficacy and tolerability of venlafaxine XR with that of
fluoxetine in a multicenter, randomized, double-blind, placebo-controlled study in depressed …

Desvenlafaxine (O-desmethylvenlafaxine) is the major active metabolite of venlafaxine.
Desvenlafaxine succinate is now undergoing active evaluation for its therapeutic efficacy in …

Objective: Sertraline may produce dual neurotransmitter effects similar to the serotonin-
norepinephrine reuptake inhibitors (SNRIs); however, it has been tested against an SNRI in …

Background Duloxetine and venlafaxine extended release (venlafaxine XR) are SNRIs
indicated for the treatment of MDD. This study addresses whether duloxetine and …