Acute inflammatory reactions, in contrast to chronic inflammatory reactions, are usually self-
limiting and resolve. We have investigated the resolving phase of a number of immune and …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

The termination of inflammation is governed by endogenous molecules collectively referred
to as 'mediators of resolution'of inflammation. There is now strong evidence to suggest that …

A recent focus meeting on Controlling Acute Inflammation was held in London, April 27-28,
2006, organized by DW Gilroy and SD Brain for the British Pharmacology Society. We …

Inflammation is a beneficial host reaction to tissue damage and has the essential primary
purpose of restoring tissue homeostasis. Inflammation plays a major role in containing and …

Acute inflammation normally resolves by mechanisms that have remained somewhat
elusive. Emerging evidence now suggests that an active, coordinated program of resolution …

The goal of treating chronic inflammatory diseases must be to inhibit persistent inflammation
and restore tissue function. To achieve this we need to improve our understanding of the …

Highlights•Inflammation is a physiological process which restores tissue homeostasis.•
Unresolved inflammation can contribute to the pathogenesis of chronic inflammatory …

Abstract Treatment of inflammatory diseases today is largely based on interrupting the
synthesis or action of mediators that drive the host's response to injury. Non-steroidal anti …

Abstract In 2012, Nature Reviews Immunology organized a conference that brought together
scientists and clinicians from both academia and industry to discuss one of the most …