[HTML][HTML] RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung …

S Gong, X Qu, S Yang, S Zhou… - International …, 2019 - spandidos-publications.com
Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

Identification of RFC5 as a novel potential prognostic biomarker in lung cancer through bioinformatics analysis

M Wang, T Xie, Y Wu, Q Yin, S Xie… - Oncology …, 2018 - spandidos-publications.com
Lung cancer is the leading cause of mortalities among all types of cancer. Therefore, the
screening of biomarkers that are related with the progression of lung cancer is crucial for …

RFC4 promotes the progression and growth of Oral Tongue squamous cell carcinoma in vivo and vitro

J Zhang, L Wang, X Xie - Journal of clinical laboratory analysis, 2021 - Wiley Online Library
Objective Currently, many studies have found that RFC4 was up‐regulated in various
cancers, and related to the progression and development. While the effects of RFC4 in oral …

RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker

Y Jiang, X Hu, M Pang, Y Huang, B Ren… - Oncology …, 2023 - spandidos-publications.com
The present study aimed to investigate the role and mechanism of action of ribonucleotide
reductase M2 (RRM2) in lung adenocarcinoma and its potential as a therapeutic target. Data …

Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma in vitro and in vivo

S Guan, L Feng, J Wei, G Wang, L Wu - Frontiers of Medicine, 2023 - Springer
Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and
Southeast Asia. Although patients benefit from the main NPC treatments (eg, radiotherapy …

Up-regulated RFC2 predicts unfavorable progression in hepatocellular carcinoma

Z Ji, J Li, J Wang - Hereditas, 2021 - Springer
Abstract Background Replication factor C (RFC) is closely related to tumor progression and
metastasis. However, the functional significance of RFC2 in hepatocellular carcinoma …

LncRNA FEZF1-AS1 enhances epithelial-mesenchymal transition (EMT) through suppressing E-cadherin and regulating WNT pathway in non-small cell lung cancer …

R He, F hu Zhang, N Shen - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Objective Recent discoveries verify that long non-coding RNAs (lncRNAs) are important
functional regulators involved in non-small cell lung cancer (NSCLC) progression. However …

PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2

J Meng, X Chen, Z Han - BMC Pulmonary Medicine, 2021 - Springer
Background To investigate the role and its potential mechanism of 6-phosphofructo-2-
kinase/fructose-2, 6-bisphosphatase 4 (PFKFB4) in lung adenocarcinoma. Methods Co …

Knockdown of GTF2E2 inhibits the growth and progression of lung adenocarcinoma via RPS4X in vitro and in vivo

G Bi, D Zhu, Y Bian, Y Huang, C Zhan, Y Yang… - Cancer cell …, 2021 - Springer
Background Lung adenocarcinoma (LUAD) is one of the most common malignancies
worldwide. However, the molecular mechanism of LUAD tumorigenesis and development …

RFC2 promotes aerobic glycolysis and progression of colorectal cancer

F Lou, M Zhang - BMC gastroenterology, 2023 - Springer
Background Replication factor C subunit 2 (RFC2) participates in the growth and metastasis
of various malignancies. Our study investigated the roles of RFC2 in colorectal cancer …