Mechanisms of eukaryotic transcription termination at a glance

J Xie, D Libri, O Porrua - Journal of cell science, 2023 - journals.biologists.com
Transcription termination is the final step of a transcription cycle, which induces the release
of the transcript at the termination site and allows the recycling of the polymerase for the next …

[PDF][PDF] Mechanism of transcription termination by RNA polymerase III utilizes a non-template strand sequence-specific signal element

AG Arimbasseri, RJ Maraia - Molecular cell, 2015 - cell.com
Understanding the mechanism of transcription termination by a eukaryotic RNA polymerase
(RNAP) has been limited by lack of a characterizable intermediate that reflects transition …

[PDF][PDF] Knowing when to stop: transcription termination on protein-coding genes by eukaryotic RNAPII

JB Rodríguez-Molina, S West, LA Passmore - Molecular cell, 2023 - cell.com
Gene expression is controlled in a dynamic and regulated manner to allow for the consistent
and steady expression of some proteins as well as the rapidly changing production of other …

The transcription cycle in eukaryotes: from productive initiation to RNA polymerase II recycling

J Shandilya, SGE Roberts - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
The cycle of eukaryotic transcription, from initiation to elongation and termination is
regulated at multiple steps. Coordinated action of regulatory factors keeps in check the …

A high density of cis-information terminates RNA Polymerase III on a 2-rail track

AG Arimbasseri, RJ Maraia - RNA biology, 2016 - Taylor & Francis
Transcription termination delineates the 3′ ends of transcripts, prevents otherwise runaway
RNA polymerase (RNAP) from intruding into downstream genes and regulatory elements …

[PDF][PDF] DNA-directed termination of RNA polymerase II transcription

Z Han, GA Moore, R Mitter, DL Martinez, L Wan… - Molecular cell, 2023 - cell.com
Summary RNA polymerase II (RNAPII) transcription involves initiation from a promoter,
transcriptional elongation through the gene, and termination in the terminator region. In …

Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo

K Rijal, RJ Maraia - PLoS genetics, 2016 - journals.plos.org
The ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation
is critical for abundant tRNA production during cellular proliferation, development and …

Transcription termination by nuclear RNA polymerases

P Richard, JL Manley - Genes & development, 2009 - genesdev.cshlp.org
Gene transcription in the cell nucleus is a complex and highly regulated process.
Transcription in eukaryotes requires three distinct RNA polymerases, each of which employs …

[PDF][PDF] Roadblock termination by reb1p restricts cryptic and readthrough transcription

J Colin, T Candelli, O Porrua, J Boulay, C Zhu… - Molecular cell, 2014 - cell.com
Widely transcribed compact genomes must cope with the major challenge of frequent
overlapping or concurrent transcription events. Efficient and timely transcription termination …

How to stop: the mysterious links among RNA polymerase II occupancy 3′ of genes, mRNA 3′ processing and termination

K Anamika, À Gyenis, L Tora - Transcription, 2013 - Taylor & Francis
Eukaryotic genes are transcribed by RNA polymerase II (RNAP II) through cycles of
initiation, elongation and termination. Termination remains the least understood stage of …