Background In patients with suspected coronary artery disease (CAD), myocardial perfusion
is assessed under rest and pharmacological stress to identify ischemia. Splenic switch‐off …

Purpose To investigate the pharmacology and potential clinical utility of splenic switch-off to
identify understress in adenosine perfusion cardiac magnetic resonance (MR) imaging …

Background Inadequate coronary adenosine response is a potential cause for false
negative ischemia testing. Recently, the splenic switch-off (SSO) sign has been identified as …

Aims Adenosine can induce splenic vasoconstriction (splenic switch-off, SSO). In this study,
we aim to evaluate the utility of identifying a lack of SSO for detecting false-negative …

Background Perfusion cardiovascular magnetic resonance (CMR) performed with
inadequate adenosine stress leads to false-negative results and suboptimal clinical …

Purpose To determine the feasibility of measuring increases in myocardial blood flow (MBF)
and myocardial perfusion reserve (MPR) on a per‐segment basis using arterial spin labeled …

Purpose Transit delay is a potential source of error in cardiac arterial spin‐labeled (ASL) in
heart failure or with collateral circulation. This study demonstrates the feasibility of using …

Purpose Although arterial spin labeling (ASL) has become a routinely performed method in
the rodent heart, its application to the human heart remains challenged by low tissue blood …

Background The sensitivity of adenosine perfusion CMR is reduced by false negative scans,
with up to 50% resulting from inadequate pharmacological stress. Without a robust …

Background Evaluation of sufficient adenosine response constitutes a significant challenge
in myocardial perfusion imaging (MPI). Splenic switch-off in MPI studies denotes a visually …