Brown and brite: the fat soldiers in the anti-obesity fight

S Srivastava, RL Veech - Frontiers in physiology, 2019 - frontiersin.org
Brown adipose tissue (BAT) is proposed to maintain thermal homeostasis through
dissipation of chemical energy as heat by the uncoupling proteins (UCPs) present in their …

Exercise training in obese rats does not induce browning at thermoneutrality and induces a muscle-like signature in brown adipose tissue

P Aldiss, JE Lewis, I Lupini, I Bloor… - Frontiers in …, 2020 - frontiersin.org
Aim: Exercise training elicits diverse effects on brown (BAT) and white adipose tissue (WAT)
physiology in rodents housed below their thermoneutral zone (ie, 28–32° C). In these …

Effects of exercise intensity on white adipose tissue browning and its regulatory signals in mice

R Tanimura, L Kobayashi, T Shirai… - Physiological …, 2022 - Wiley Online Library
Adipose tissue has been classified into white adipose tissue (WAT), brown adipose tissue
(BAT), and beige adipose tissue the latter of which is produced as WAT changes into BAT …

Brown fat fuel utilization and thermogenesis

KL Townsend, YH Tseng - Trends in Endocrinology & Metabolism, 2014 - cell.com
Brown adipose tissue (BAT) dissipates energy as heat to maintain optimal thermogenesis
and to contribute to energy expenditure in rodents and possibly humans. The energetic …

Thermogenic brown and beige/brite adipogenesis in humans

R Cereijo, M Giralt, F Villarroya - Annals of medicine, 2015 - Taylor & Francis
Evidence from rodents established an important role of brown adipose tissue (BAT) in
energy expenditure. Moreover, to sustain thermogenesis, BAT has been shown to be a …

Human brown adipose tissue: regulation and anti-obesity potential

M Saito - Endocrine journal, 2014 - jstage.jst.go.jp
Brown adipose tissue (BAT) is the site of sympathetically activated adaptive thermognenesis
during cold exposure and after hyperphagia, thereby controlling whole-body energy …

The significance of beige and brown fat in humans

FW Kiefer - Endocrine connections, 2017 - ec.bioscientifica.com
Promotion of brown adipose tissue (BAT) activity or browning of white adipose tissue has
shown great potential as anti-obesity strategy in numerous preclinical models. The discovery …

Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

MJ Vosselman, J Hoeks, B Brans… - International Journal of …, 2015 - nature.com
Results: Cold-induced BAT activity was significantly lower in athletes, and no differences in
gene expression of classical brown and beige adipocyte markers were detected in …

The impact of moderate-intensity continuous or high-intensity interval training on adipogenesis and browning of subcutaneous adipose tissue in obese male rats

M Khalafi, H Mohebbi, ME Symonds, P Karimi, A Akbari… - Nutrients, 2020 - mdpi.com
This study compares the effect of two types of exercise training, ie, moderate-intensity
continuous training (MICT) or high-intensity interval training (HIIT) on the browning of …

The effects of exercise on white and brown adipose tissue cellularity, metabolic activity and remodeling

JD Garritson, S Boudina - Frontiers in physiology, 2021 - frontiersin.org
Emerging evidence suggests a significant functional role of adipose tissue in maintaining
whole-body metabolic health. It is well established that obesity leads to compositional and …