In vitro brown and “brite”/“beige” adipogenesis: human cellular models and molecular aspects

GE Beranger, M Karbiener, V Barquissau… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Brown adipose tissue (BAT) has long been thought to be absent or very scarce in human
adults so that its contribution to energy expenditure was not considered as relevant. The …

White, brown, beige/brite: different adipose cells for different functions?

M Giralt, F Villarroya - Endocrinology, 2013 - academic.oup.com
Brown adipose tissue (BAT) is a major site of nonshivering thermogenesis in mammals.
Rodent studies indicated that BAT thermogenic activity may protect against obesity. Recent …

Contribution of brown adipose tissue to human energy metabolism

R Fernández-Verdejo, KL Marlatt, E Ravussin… - Molecular aspects of …, 2019 - Elsevier
The present “obesogenic'environment has favored excessive energy intake resulting in the
current obesity epidemic and its associated diseases. The epidemic has incentivized …

Brown adipose tissue: an update on recent findings

KL Marlatt, E Ravussin - Current obesity reports, 2017 - Springer
Abstract Purpose of Review New treatment approaches to weight loss and weight loss
maintenance in humans are critical. Given its potential role in stimulating energy …

Increased brown adipose tissue oxidative capacity in cold-acclimated humans

DP Blondin, SM Labbé, HC Tingelstad… - The Journal of …, 2014 - academic.oup.com
Context: Recent studies examining brown adipose tissue (BAT) metabolism in adult humans
have provided convincing evidence of its thermogenic potential and role in clearing …

Is activation of human brown adipose tissue a viable target for weight management?

KL Marlatt, KY Chen… - American Journal of …, 2018 - journals.physiology.org
To date, human studies show that brown adipose tissue (BAT) contributes a small yet highly
variable amount to overall energy expenditure. No studies have shown a decrease in body …

Different metabolic responses of human brown adipose tissue to activation by cold and insulin

J Orava, P Nuutila, ME Lidell, V Oikonen, T Noponen… - Cell metabolism, 2011 - cell.com
We investigated the metabolism of human brown adipose tissue (BAT) in healthy subjects by
determining its cold-induced and insulin-stimulated glucose uptake and blood flow …

Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans

M Chondronikola, E Volpi, E Børsheim, C Porter… - Diabetes, 2014 - Am Diabetes Assoc
Brown adipose tissue (BAT) has attracted scientific interest as an antidiabetic tissue owing to
its ability to dissipate energy as heat. Despite a plethora of data concerning the role of BAT …

Exercise and browning of white adipose tissue–a translational perspective

MCK Severinsen, C Schéele, BK Pedersen - Current Opinion in …, 2020 - Elsevier
Browning of white adipose tissue is a cold-induced phenomenon in rodents, constituted by
the differentiation of a subset of thermogenic adipocytes among existing white adipocytes …

Many ways to Rome: exercise, cold exposure and diet—do they all affect BAT activation and WAT browning in the same manner?

AK Scheel, L Espelage, A Chadt - International journal of molecular …, 2022 - mdpi.com
The discovery of functional brown adipose tissue (BAT) in adult humans and the possibility
to recruit beige cells with high thermogenic potential within white adipose tissue (WAT) …