Active brown adipose tissue is associated with a healthier metabolic phenotype in obesity

CT Herz, OC Kulterer, M Prager, C Schmöltzer… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is associated with increasing cardiometabolic morbidity and mortality rates
worldwide. Not everyone with obesity, however, develops metabolic complications. Brown …

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

L Cheng, J Wang, H Dai, Y Duan, Y An, L Shi, Y Lv… - Adipocyte, 2021 - Taylor & Francis
Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

Brown adipose tissue: a human perspective

MR Boon, WD van Marken Lichtenbelt - Metabolic Control, 2016 - Springer
Since 2009, the presence of brown adipose tissue (BAT) in adult humans has been
irrefutably proven. It is estimated that active BAT can contribute up to 2.5–5% of resting …

Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders

S Roman, A Agil, M Peran, E Alvaro-Galue… - Translational …, 2015 - Elsevier
In humans, 2 functionally different types of adipose tissue coexist: white adipose tissue
(WAT) and brown adipose tissue (BAT). WAT is involved in energy storage, whereas BAT is …

[HTML][HTML] Exercise training induces depot-specific adaptations to white and brown adipose tissue

AC Lehnig, RS Dewal, LA Baer, KM Kitching… - IScience, 2019 - cell.com
Exercise affects whole-body metabolism through adaptations to various tissues, including
adipose tissue (AT). Recent studies investigated exercise-induced adaptations to AT …

[PDF][PDF] Brown adipose tissue as a regulator of energy expenditure and body fat in humans

M Saito - Diabetes & metabolism journal, 2013 - synapse.koreamed.org
Brown adipose tissue (BAT) is recognized as the major site of sympathetically activated
nonshivering thermogenesis during cold exposure and after spontaneous hyperphagia …

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans

J Orava, P Nuutila, T Noponen, R Parkkola, T Viljanen… - …, 2013 - Wiley Online Library
Objective Inactive brown adipose tissue (BAT) may predispose to weight gain. This study
was designed to measure metabolism in the BAT of obese humans, and to compare it to that …

Interleukin-6 released from differentiating human beige adipocytes improves browning

E Kristóf, Á Klusóczki, R Veress, A Shaw… - Experimental cell …, 2019 - Elsevier
Brown and beige adipocytes contribute significantly to the regulation of whole body energy
expenditure and systemic metabolic homeostasis not exclusively by thermogenesis through …

Activation and recruitment of brown adipose tissue as anti-obesity regimens in humans

T Yoneshiro, M Saito - Annals of medicine, 2015 - Taylor & Francis
Brown adipose tissue (BAT) is the site of sympathetically activated adaptive thermogenesis
during cold exposure and after hyperphagia, thereby controlling whole-body energy …

[HTML][HTML] Adipose tissue browning in mice and humans

CT Herz, FW Kiefer - Journal of Endocrinology, 2019 - joe.bioscientifica.com
In the midst of an obesity epidemic, the promotion of brown adipose tissue (BAT) function
and the browning of white adipose tissue (WAT) have emerged as promising therapeutic …