Gene therapy: Comprehensive overview and therapeutic applications
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
[HTML][HTML] Current progress in gene delivery technology based on chemical methods and nano-carriers
L Jin, X Zeng, M Liu, Y Deng, N He - Theranostics, 2014 - ncbi.nlm.nih.gov
Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …
transfer include three major groups: viral, physical and chemical methods. This review …
A review of the tortuous path of nonviral gene delivery and recent progress
Gene therapy encompasses the transfer of exogenous genetic materials into the patient's
target cells to treat or prevent diseases. Nevertheless, the transfer of genetic material into …
target cells to treat or prevent diseases. Nevertheless, the transfer of genetic material into …
[PDF][PDF] Vectors and delivery systems in gene therapy
Gene therapy provides modern medicine with new perspectives that were unthinkable two
decades ago. Progress in molecular biology and, especially, molecular medicine is now …
decades ago. Progress in molecular biology and, especially, molecular medicine is now …
[HTML][HTML] Non viral vectors in gene therapy-an overview
M Ramamoorth, A Narvekar - Journal of clinical and diagnostic …, 2015 - ncbi.nlm.nih.gov
Non-viral vectors are simple in theory but complex in practice. Apart from intra cellular and
extracellular barriers, number of other challenges also needs to be overcome in order to …
extracellular barriers, number of other challenges also needs to be overcome in order to …
[HTML][HTML] Delivery systems for gene therapy
S Mali - Indian journal of human genetics, 2013 - ncbi.nlm.nih.gov
The structure of DNA was unraveled by Watson and Crick in 1953, and two decades later
Arber, Nathans and Smith discovered DNA restriction enzymes, which led to the rapid …
Arber, Nathans and Smith discovered DNA restriction enzymes, which led to the rapid …
[HTML][HTML] Novel gene delivery systems
SB Manjila, JN Baby, EN Bijin… - International journal …, 2013 - ncbi.nlm.nih.gov
Gene therapy is an emerging field in medical and pharmaceutical sciences because of its
potential in treating chronic diseases like cancer, viral infections, myocardial infarctions, and …
potential in treating chronic diseases like cancer, viral infections, myocardial infarctions, and …
[HTML][HTML] Appraisal for the potential of viral and nonviral vectors in gene therapy: A review
Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …
Gene therapy and DNA delivery systems
Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …
such as cancer and genetic disorders. The main problem limiting the application of this …
In pursuit of new developments for gene therapy of human diseases
G Palu, R Bonaguro, A Marcello - Journal of biotechnology, 1999 - Elsevier
Gene therapy aims at transferring a therapeutic gene into human somatic cells in order to
treat a disease. Originally addressed to hereditary genetic disorders, gene therapy has …
treat a disease. Originally addressed to hereditary genetic disorders, gene therapy has …