Structural changes of atrial myocardium during chronic atrial fibrillation

VLJL Thijssen, J Ausma, GS Liu, MA Allessie… - Cardiovascular …, 2000 - Elsevier
Of all known arrhythmia's, atrial fibrillation (AF) is the most often met in the clinical setting
and it is associated with an increase in mortality risk. Several risk factors for AF have been …

Atrial fibrillation from the pathologist's perspective

D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …

[HTML][HTML] Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

[HTML][HTML] Fibrosis in atrial fibrillation–role of reactive species and MPO

K Friedrichs, S Baldus, A Klinke - Frontiers in physiology, 2012 - frontiersin.org
Atrial fibrosis with enhanced turnover and deposition of matrix proteins leads to
inhomogeneous atrial electrical conduction and gives rise to electrical reentry circuits …

Atrial fibrillation: effects beyond the atrium?

RS Wijesurendra, B Casadei - Cardiovascular research, 2015 - academic.oup.com
Atrial fibrillation (AF) is the most common sustained clinical arrhythmia and is associated
with significant morbidity, mostly secondary to heart failure and stroke, and an estimated two …

Association of left atrial fibrosis detected by delayed-enhancement magnetic resonance imaging and the risk of stroke in patients with atrial fibrillation

M Daccarett, TJ Badger, N Akoum, NS Burgon… - Journal of the American …, 2011 - jacc.org
Objectives: This study tried to determine the association between left atrial (LA) fibrosis,
detected using delayed-enhanced magnetic resonance imaging (DE-MRI), and the …

Age and sex differences in atrial fibrosis among patients with atrial fibrillation

N Akoum, C Mahnkopf, EG Kholmovski… - EP …, 2018 - academic.oup.com
Aim Age and female sex are associated with a higher risk of stroke in atrial fibrillation (AF).
We sought to determine whether advancing age and female sex are associated with higher …

[HTML][HTML] Relation of echocardiographic markers of left atrial fibrosis to atrial fibrillation burden

M Leung, R Abou, PJ van Rosendael… - The American Journal of …, 2018 - Elsevier
In patients with atrial fibrillation (AF), left atrial (LA) fibrosis is a major determinant of the
progression to, and burden of AF. LA reservoir strain and total atrial conduction time (PA …

Role of inflammatory signaling in atrial fibrillation

L Scott Jr, N Li, D Dobrev - International journal of cardiology, 2019 - Elsevier
Atrial fibrillation (AF), the most prevalent arrhythmia, is often associated with enhanced
inflammatory response. Emerging evidence points to a causal role of inflammatory signaling …

Fibrotic atrial cardiomyopathy, atrial fibrillation, and thromboembolism: mechanistic links and clinical inferences

BJ Hirsh, RS Copeland-Halperin, JL Halperin - Journal of the American …, 2015 - jacc.org
The association of atrial fibrillation (AF) with ischemic stroke has long been recognized; yet,
the pathogenic mechanisms underlying this relationship are incompletely understood …