Inflammatory pain is caused by peripheral tissue injury and inflammation. Inflammation
leads to peripheral sensitization, which may further cause central sensitization, resulting in …

Neurogenic pain rises because of nervous system damage or dysfunction and is the most
difficult to treat among other pathological pains. Acupuncture has been reported as a great …

Although acupuncture, especially electroacupuncture (EA) is widely used to treat pain, its
mechanisms have not been completely understood. In the present paper, we review the …

Inflammation plays a significant role in the occurrence and development of multiple
diseases. This study comprehensively reviews and presents literature from the last five …

Acupuncture has been used for millennia to treat allergic diseases including both
intermittent rhinitis and persistent rhinitis. Besides the research on the efficacy and safety of …

Nociceptive signals are transmitted by peripheral afferents to the central nervous system
under pain condition, a process that involves various neurotransmitters and pathways …

Although pain is regarded as a global public health priority, analgesic therapy remains a
significant challenge. Pain is a hypersensitivity state caused by peripheral and central …

Neuropathic pain, caused by a lesion or disease of the somatosensory system, is common
and distressing. In view of the high human and economic burden, more effective treatment …

An increasing number of studies have demonstrated the underlying mechanisms by which
acupuncture therapy mediates both local and systemic immunomodulation. However, the …

Pain can trigger central amplification called central sensitization, which ultimately results in
hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic …