[PDF][PDF] Human genetics: the evolving story of FOXP2

SE Fisher - Current Biology, 2019 - cell.com
Human Genetics: The Evolving Story of FOXP2 Page 1 7. Graybiel, AM, and Ragsdale, CW,
Jr. (1978). Histochemically distinct compartments in the striatum of human, monkeys, and …

[PDF][PDF] Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits

KD MacDermot, E Bonora, N Sykes, AM Coupe… - The American Journal of …, 2005 - cell.com
FOXP2, the first gene to have been implicated in a developmental communication disorder,
offers a unique entry point into neuromolecular mechanisms influencing human speech and …

Molecular evolution of FOXP2, a gene involved in speech and language

W Enard, M Przeworski, SE Fisher, CSL Lai, V Wiebe… - Nature, 2002 - nature.com
Abstract Language is a uniquely human trait likely to have been a prerequisite for the
development of human culture. The ability to develop articulate speech relies on …

Generation of mice with a conditional Foxp2 null allele

CA French, M Groszer, C Preece, AM Coupe… - genesis, 2007 - Wiley Online Library
Disruptions of the human FOXP2 gene cause problems with articulation of complex speech
sounds, accompanied by impairment in many aspects of language ability. The FOXP2/Foxp2 …

FOXP2 as a molecular window into speech and language

SE Fisher, C Scharff - Trends in Genetics, 2009 - cell.com
Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …

[HTML][HTML] A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment

R Lozano, A Vino, C Lozano, SE Fisher… - European journal of …, 2015 - nature.com
FOXP1 (forkhead box protein P1) is a transcription factor involved in the development of
several tissues, including the brain. An emerging phenotype of patients with protein …

Foxp2

R Nudel, DF Newbury - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
The forkhead box P2 gene, designated FOXP2, is the first gene implicated in a speech and
language disorder. Since its discovery, many studies have been carried out in an attempt to …

Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder

E Sollis, SA Graham, A Vino, H Froehlich… - Human molecular …, 2016 - academic.oup.com
De novo disruptions of the neural transcription factor FOXP1 are a recently discovered, rare
cause of sporadic intellectual disability (ID). We report three new cases of FOXP1-related …

[PDF][PDF] De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment

FF Hamdan, H Daoud, D Rochefort, A Piton… - The American Journal of …, 2010 - cell.com
Heterozygous mutations in FOXP2, which encodes a forkhead transcription factor, have
been shown to cause developmental verbal dyspraxia and language impairment. FOXP2 …

'Speech Gene'Tied to Modern Humans

M Balter - 2002 - science.org
The ability to communicate through spoken language is the trait that best sets humans apart
from other animals, most human origins researchers say. Last year the community was …