Disease progression and mortality with untreated HIV infection: Evidence synthesis of HIV seroconverter cohorts, antiretroviral treatment clinical cohorts and …
R Glaubius, N Kothegal, S Birhanu… - Journal of the …, 2021 - Wiley Online Library
Introduction Model‐based estimates of key HIV indicators depend on past epidemic trends
that are derived based on assumptions about HIV disease progression and mortality in the …
that are derived based on assumptions about HIV disease progression and mortality in the …
[HTML][HTML] Differences in HIV natural history among African and non-African seroconverters in Europe and seroconverters in sub-Saharan Africa
N Pantazis, C Morrison, PN Amornkul, C Lewden… - PloS one, 2012 - journals.plos.org
Introduction It is unknown whether HIV treatment guidelines, based on resource-rich country
cohorts, are applicable to African populations. Methods We estimated CD4 cell loss in ART …
cohorts, are applicable to African populations. Methods We estimated CD4 cell loss in ART …
[HTML][HTML] Joint estimation of CD4+ cell progression and survival in untreated individuals with HIV-1 infection
TD Mangal - Aids, 2017 - journals.lww.com
Objective: We compiled the largest dataset of seroconverter cohorts to date from 25
countries across Africa, North America, Europe, and Southeast/East (SE/E) Asia to …
countries across Africa, North America, Europe, and Southeast/East (SE/E) Asia to …
CD4: CD8 ratio and CD8 count as prognostic markers for mortality in human immunodeficiency virus–infected patients on antiretroviral therapy: the Antiretroviral …
Background We investigated whether CD4: CD8 ratio and CD8 count were prognostic for all-
cause, AIDS, and non-AIDS mortality in virologically suppressed patients with high CD4 …
cause, AIDS, and non-AIDS mortality in virologically suppressed patients with high CD4 …
Mortality according to CD4 count at start of combination antiretroviral therapy among HIV-infected patients followed for up to 15 years after start of treatment …
MT May, JJ Vehreschild, A Trickey… - Clinical Infectious …, 2016 - academic.oup.com
Background. CD4 count at start of combination antiretroviral therapy (ART) is strongly
associated with short-term survival, but its association with longer-term survival is less well …
associated with short-term survival, but its association with longer-term survival is less well …
Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: an observational cohort study
Summary Background Measures of CD4 T-cell count and HIV-1 plasma viral load before
antiretroviral therapy are proxies for virulence. Whether these proxies are changing over …
antiretroviral therapy are proxies for virulence. Whether these proxies are changing over …
[HTML][HTML] Estimation of time of HIV seroconversion using a modified CD4 depletion model
VD Lima, L Wang, P Sereda, T McLinden, R Barrios… - PLoS …, 2021 - journals.plos.org
Introduction Several methods have been proposed to estimate the time of HIV
seroconversion, including those based on CD4 cell depletion models. However, previous …
seroconversion, including those based on CD4 cell depletion models. However, previous …
Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics
MT May, RS Hogg, AC Justice… - International journal …, 2012 - academic.oup.com
Background HIV cohort collaborations, which pool data from diverse patient cohorts, have
provided key insights into outcomes of antiretroviral therapy (ART). However, the extent of …
provided key insights into outcomes of antiretroviral therapy (ART). However, the extent of …
[HTML][HTML] Mortality of treated HIV-1 positive individuals according to viral subtype in Europe and Canada: collaborative cohort analysis
Antiretroviral Therapy Cohort Collaboration (ART-CC… - Aids, 2016 - journals.lww.com
Objectives: To estimate prognosis by viral subtype in HIV-1-infected individuals from start of
antiretroviral therapy (ART) and after viral failure. Design: Collaborative analysis of data from …
antiretroviral therapy (ART) and after viral failure. Design: Collaborative analysis of data from …
[HTML][HTML] CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy
Objectives Immune non-responders (INR) have poor CD4 recovery and are associated with
increased risk of serious events despite antiretroviral therapy (ART). A clinically relevant …
increased risk of serious events despite antiretroviral therapy (ART). A clinically relevant …