Efficient Synthesis of Phosphorus/Nitrogen‐Containing Chrysin Derivatives via Classic Reactions

Z Zeng, S Liu, W Luo, J Liang, AY Peng - ChemistrySelect, 2021 - Wiley Online Library
Chrysin is a widely distributed natural flavonoid with broad biological activities, but its poor
bioavailability and insufficient efficacy limit its clinical applications. Based on prodrug and …

Synthesis of the novel phosphoramidate derivatives of chrysin

X Chen, J Yuan, S Zhang, L Qu… - Phosphorus, Sulfur, and …, 2010 - Taylor & Francis
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Synthesis of New Types of N‐Arylpiperazine Phosphoramide Analogues of Chrysin

XL Chen, XY Li, JW Yuan, ZB Qu… - Journal of the …, 2010 - Wiley Online Library
Several N‐arylpiperazine phosphoramide analogues of chrysin are synthesized through a
facile phosphorylated reaction for the first time. Their structures are elucidated by NMR, ESI …

Design, Synthesis, and In vitro Anticancer Activity of Novel Chrysin Derivatives

Q Yu, B Huang, Y Ling - Letters in Drug Design & Discovery, 2023 - ingentaconnect.com
Background: Cancer is a serious threaten to human life, and drug developers are pushing
hard to discover potent anticancer agents. Pyrimidine and flavonoids are both attractive …

Development of a concise synthesis of the flavonoid chrysin

Q Wang, W Cui, J Yang, B Yang - Journal of Chemical …, 2015 - journals.sagepub.com
Two novel routes for the synthesis of the flavonoid chrysin are described. In the first, 3, 5-
dimethoxyphenol (taxicatigenin) was converted to 2-hydroxy-4, 6-dimethoxyacetophenone …

Synthetic derivatives of chrysin and their biological activities

Y Liu, X Song, J He, X Zheng, H Wu - Medicinal Chemistry Research, 2014 - Springer
Chrysin is one of flavones constituents of Orocylumineicum vent. It has been a hot spot as a
potential chemopreventive agent and as a natural molecule with numerous biological …

Fluorine-containing chrysin derivatives: synthesis and biological activity

Y Zhu, X Yao, J Long, R Li, Y Liu… - Natural Product …, 2019 - journals.sagepub.com
Chrysin, a flavonoid, has played a great role in the fields of anticancer, antibacterial, and
antiviral drug discovery. A large number of chrysin derivatives have been synthesized …

Synthesis and in vitro anticancer evaluation of novel chrysin and 7-aminochrysin derivatives

S Mayer, P Keglevich, P Ábrányi-Balogh, Á Szigetvári… - Molecules, 2020 - mdpi.com
Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report
the synthesis of new chrysin derivatives alkylated with N-phenylchloroacetamides in position …

Chrysin: A polyedric flavone as a tool to explore new phytotherapeutic applications and drug design

F Falbo, F Aiello - Archiv der Pharmazie, 2023 - Wiley Online Library
In the field of pharmaceutical research, a branch that has become more and more interesting
is phytochemistry. Among phytochemicals, flavonoids have been studied a lot over the past …

Synthesis of novel phosphorylated chrysin derivatives by 1, 3-dipolar cycloaddition reaction

S Zhu, Y Zhang, P Li, W Bi, X Chen… - Phosphorus, Sulfur, and …, 2017 - Taylor & Francis
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reaction Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …